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ClinicalTrials.gov 3 recruiting now early-phase tilt small index

Endometrial Adenocarcinoma: early-phase trial registry

3 of 14 indexed Endometrial Adenocarcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 3 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Endometrial Adenocarcinoma: 14 US clinical trials tracked, 3 recruiting.

Endometrial Adenocarcinoma is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 6 of these trials.

Enrollment posture brief

Registry condition endometrial-adenocarcinoma

OPEN 3 | RECR 21% | LATE 0 | EARLY 13 | RANK #1230 | SPON 6

Nearest open-share peer: Cervical Adenocarcinoma (21% recruiting · 14 trials)

Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Endometrial Adenocarcino (th…21%Abscess7.1%
Open-enrollment share among volume-matched conditions near Endometrial Adenocarcinoma

Endometrial Adenocarcinoma lists 3 open slots (21% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Endometrial Adenocarcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Endometrial Adenocarcinoma is recruiting below its size-band peers.

    3 of 14 indexed trials (21.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Endometrial Adenocarcinoma research.

    National Cancer Institute (NCI) accounts for 6 of 14 trials (42.9%). 6 distinct sponsors appear on at least one study for this condition label.

  3. Typical Endometrial Adenocarcinoma enrolment sits around 81 participants.

    Median target enrolment is 81 among the 14 trials that report a genuine target (sentinel values excluded). 8 of those (57.1%) plan for fewer than 100 participants.

  4. Endometrial Adenocarcinoma research is mostly interventional.

    13 interventional and 1 observational studies make up this index (92.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 29

Open and recent trials

14 total, page 1 of 1

RECRUITING Phase 2 353 participants

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

Acrivon Therapeutics

NCT05548296

RECRUITING Phase 1 100 participants

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

Apollo Therapeutics

NCT06399757

RECRUITING Phase 2 81 participants

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

National Cancer Institute (NCI)

NCT05112601

ACTIVE NOT RECRUITING Phase 2 349 participants

Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

National Cancer Institute (NCI)

NCT00977574

ACTIVE NOT RECRUITING Phase 2 288 participants

Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

National Cancer Institute (NCI)

NCT03660826

ACTIVE NOT RECRUITING Phase 1 159 participants

mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian

M.D. Anderson Cancer Center

NCT02208375

ACTIVE NOT RECRUITING Phase 1 31 participants

Niraparib and Copanlisib in Treating Patients With Recurrent Endometrial, Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

M.D. Anderson Cancer Center

NCT03586661

ACTIVE NOT RECRUITING Phase 2 24 participants

Study of BMS-986205 and Nivolumab in Endometrial Cancer or Endometrial Carcinosarcoma That Has Not Responded to Treatment

Memorial Sloan Kettering Cancer Center

NCT04106414

COMPLETED 2,824 participants

Prognostic Biomarkers in Patients With Endometrial Cancer

Gynecologic Oncology Group

NCT01208467

COMPLETED Phase 2 75 participants

Medroxyprogesterone in Treating Patients With Endometrioid Adenocarcinoma of the Uterine Corpus

Gynecologic Oncology Group

NCT00064025

COMPLETED Phase 2 37 participants

Akt Inhibitor MK2206 in Treating Patients With Recurrent or Advanced Endometrial Cancer

National Cancer Institute (NCI)

NCT01307631

COMPLETED Phase 2 37 participants

Nintedanib in Treating Patients With Recurrent or Persistent Endometrial Cancer

Gynecologic Oncology Group

NCT01225887

COMPLETED Phase 2 34 participants

Trastuzumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

National Cancer Institute (NCI)

NCT00006089

COMPLETED Phase 1 26 participants

Trametinib With or Without GSK2141795 in Treating Patients With Recurrent or Persistent Endometrial Cancer

National Cancer Institute (NCI)

NCT01935973

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 9

Named interventions

Most-linked intervention names on Endometrial Adenocarcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Laboratory Biomarker Analysis Other
7 trials
Capivasertib Drug
2 trials
Biospecimen Collection Procedure
2 trials
Medroxyprogesterone Drug
1 trials
Uprosertib Drug
1 trials
BMS- 986205 Drug
1 trials
Vistusertib Drug
1 trials
Cediranib Maleate Drug
1 trials

US sites by state

Facility locations filed on Endometrial Adenocarcinoma trials. A trial with sites in several states counts in each.

Texas 5 trials
Pennsylvania 4 trials
Georgia 4 trials
Connecticut 4 trials
California 4 trials
New York 3 trials
Illinois 3 trials
Colorado 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Endometrial Adenocarcinoma page

14 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Endometrial Adenocarcinoma condition card totals 14 registered trials; most-linked intervention Laboratory Biomarker Analysis; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.