Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Drug Use: early-phase trial registry
7 of 26 indexed Drug Use trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #627 of 28,707 conditions by registered trial count.
26 US clinical trials · 7 currently recruiting · #627 of 28,707 conditions by registered trial count
Drug Use: 26 US clinical trials tracked, 7 recruiting.
Drug Use is the subject of 26 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is University of Michigan, running 4 of these trials.
Enrollment posture brief
Registry condition drug-use
OPEN 7 | RECR 27% | LATE 1 | EARLY 3 | RANK #627 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Metabolic Syndrome (27% recruiting · 104 trials)
Drug Use lists 7 open slots (27% of 26 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Drug Use on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Drug Use is recruiting below its size-band peers.
7 of 26 indexed trials (26.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Drug Use research.
University of Michigan accounts for 4 of 26 trials (15.4%). 17 distinct sponsors appear on at least one study for this condition label.
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Typical Drug Use enrolment sits around 180 participants.
Median target enrolment is 180 among the 26 trials that report a genuine target (sentinel values excluded). 13 of those (50%) plan for fewer than 100 participants.
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Drug Use research is mostly interventional.
26 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
26 total, page 1 of 1
Mental Health in Primary Care
University of Miami
NCT05426057
Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation
Johns Hopkins University
NCT06103370
Families With Pride ("Familias Con Orgullo").
University of Miami
NCT06057337
Harm Reduction Services
NYU Langone Health
NCT05776316
Family Acceptance Project Online (Pilot RCT)
University of Michigan
NCT06839859
Developing a Positive Approach to Substance Use Prevention in North American Indian Adolescents
University of Rhode Island
NCT05380765
Lakota Family Acceptance Project
University of Michigan
NCT07326748
mHealth to Enhance & Sustain Drug Use Reduction of the QUIT BI in Primary Care
University of California, Los Angeles
NCT04935606
Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care
Johns Hopkins University
NCT04601064
A Hybrid Effectiveness Implementation Study of Latino/a Alcohol and Drug Users
Boston University Charles River Campus
NCT04771650
Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents
Johns Hopkins Bloomberg School of Public Health
NCT02904629
Acute Intervention to Reduce Distress Following Sexual Assault
Medical University of South Carolina
NCT01622855
Multimedia WORTH With Black Drug-Involved Women on Probation
Columbia University
NCT02391233
Alcohol Screening in an Ethnically Diverse Sample of Adolescents in Primary Care
RAND
NCT01797835
Prevention and Risk: Treatment With a New Emphasis on Relationships
Hunter College of City University of New York
NCT03396367
Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions
Treatment Research Institute
NCT02059005
Integrated Outpatient Treatment of Opioid Use Disorder and Severe Injection Related Infections
Laura Fanucchi
NCT04677114
Intergenerational Strengths-Based Program for American Indian Girls as They Transition to Adulthood
Johns Hopkins Bloomberg School of Public Health
NCT03900312
Drug Use and Sexual Risk Behaviors Among Emerging Adults in the ER
University of Michigan
NCT03079856
Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention
University of Michigan
NCT03855410
Testing the Effectiveness of a Graphic Novel Health Education Curriculum for Patients With Addiction
Treatment Research Institute
NCT02378181
Technology-Enhanced Peer Navigation to Improve IDUs' Engagement in HIV Care
Johns Hopkins Bloomberg School of Public Health
NCT01941108
HCV Seek, Test and Rapid Treatment for Young PWID
Weill Medical College of Cornell University
NCT03627546
Y2Prevent: Preventing Drug Use and HIV Through Empowerment, Social Support and Mentorship (Y2P)
Children's Hospital Los Angeles
NCT04504981
Implementation of Onsite, Rapid ART Initiation Among People Who Inject Drugs Living With HIV at Syringe Services Program
University of Miami
NCT04650269
Interventions to Improve the HIV PrEP Cascade Among Methamphetamine Users
University of Washington
NCT03584282
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Drug Use records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Drug Use trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Drug Use page
26 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 7 Drug Use trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Michigan sponsors the most Drug Use trials on record, review their full trial history before evaluating a specific study. See University of Michigan's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Drug Use condition card totals 26 registered trials; most-linked intervention Streamlined HIV Testing; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.