Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Drug Use clinical trials
Every US clinical trial registered for Drug Use — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
26 US clinical trials · 7 currently recruiting
The research picture
Drug Use has 26 registered US clinical trials, 7 of them open to new participants right now — about 27% of the total.
- 7
- recruiting participants now
- 27%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 4
- top sponsor: University of Michigan
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Mental Health in Primary Care
University of Miami
NCT05426057
Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation
Johns Hopkins University
NCT06103370
Families With Pride ("Familias Con Orgullo").
University of Miami
NCT06057337
Harm Reduction Services
NYU Langone Health
NCT05776316
Family Acceptance Project Online (Pilot RCT)
University of Michigan
NCT06839859
Developing a Positive Approach to Substance Use Prevention in North American Indian Adolescents
University of Rhode Island
NCT05380765
Lakota Family Acceptance Project
University of Michigan
NCT07326748
mHealth to Enhance & Sustain Drug Use Reduction of the QUIT BI in Primary Care
University of California, Los Angeles
NCT04935606
Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care
Johns Hopkins University
NCT04601064
A Hybrid Effectiveness Implementation Study of Latino/a Alcohol and Drug Users
Boston University Charles River Campus
NCT04771650
Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents
Johns Hopkins Bloomberg School of Public Health
NCT02904629
Acute Intervention to Reduce Distress Following Sexual Assault
Medical University of South Carolina
NCT01622855
Multimedia WORTH With Black Drug-Involved Women on Probation
Columbia University
NCT02391233
Alcohol Screening in an Ethnically Diverse Sample of Adolescents in Primary Care
RAND
NCT01797835
Prevention and Risk: Treatment With a New Emphasis on Relationships
Hunter College of City University of New York
NCT03396367
Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions
Treatment Research Institute
NCT02059005
Integrated Outpatient Treatment of Opioid Use Disorder and Severe Injection Related Infections
Laura Fanucchi
NCT04677114
Intergenerational Strengths-Based Program for American Indian Girls as They Transition to Adulthood
Johns Hopkins Bloomberg School of Public Health
NCT03900312
Drug Use and Sexual Risk Behaviors Among Emerging Adults in the ER
University of Michigan
NCT03079856
Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention
University of Michigan
NCT03855410
Testing the Effectiveness of a Graphic Novel Health Education Curriculum for Patients With Addiction
Treatment Research Institute
NCT02378181
Technology-Enhanced Peer Navigation to Improve IDUs' Engagement in HIV Care
Johns Hopkins Bloomberg School of Public Health
NCT01941108
HCV Seek, Test and Rapid Treatment for Young PWID
Weill Medical College of Cornell University
NCT03627546
Y2Prevent: Preventing Drug Use and HIV Through Empowerment, Social Support and Mentorship (Y2P)
Children's Hospital Los Angeles
NCT04504981
Implementation of Onsite, Rapid ART Initiation Among People Who Inject Drugs Living With HIV at Syringe Services Program
University of Miami
NCT04650269
Interventions to Improve the HIV PrEP Cascade Among Methamphetamine Users
University of Washington
NCT03584282
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Drug Use Trial Landscape
ClinicalTrials.gov lists 26 US studies indexed under Drug Use, and 7 of those are currently open to recruitment — roughly 27% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Drug Use shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Drug Use is led by University of Michigan with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 26 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Drug Use?
PlainTrial tracks 26 US clinical trials for Drug Use, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Drug Use?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.