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ClinicalTrials.gov 7 recruiting now official registry

Drug Use clinical trials

7 of 26 indexed Drug Use trials are currently recruiting.

26 US clinical trials · 7 currently recruiting

Drug Use is the subject of 26 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is University of Michigan, running 4 of these trials.

The research picture

Drug Use has 26 registered US clinical trials, 7 of them open to new participants right now, about 27% of the total.

7
recruiting participants now
27%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
4
top sponsor: University of Michigan
Phase 11Phase 22Phase 41

Active & Recent Trials

26 total, page 1 of 1

RECRUITING NA 468 participants

Mental Health in Primary Care

University of Miami

NCT05426057

RECRUITING NA 360 participants

Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

Johns Hopkins University

NCT06103370

RECRUITING NA 306 participants

Families With Pride ("Familias Con Orgullo").

University of Miami

NCT06057337

RECRUITING NA 200 participants

Harm Reduction Services

NYU Langone Health

NCT05776316

RECRUITING Phase 2 180 participants

Family Acceptance Project Online (Pilot RCT)

University of Michigan

NCT06839859

RECRUITING NA 60 participants

Developing a Positive Approach to Substance Use Prevention in North American Indian Adolescents

University of Rhode Island

NCT05380765

RECRUITING NA 28 participants

Lakota Family Acceptance Project

University of Michigan

NCT07326748

ACTIVE NOT RECRUITING NA 458 participants

mHealth to Enhance & Sustain Drug Use Reduction of the QUIT BI in Primary Care

University of California, Los Angeles

NCT04935606

ACTIVE NOT RECRUITING NA 405 participants

Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care

Johns Hopkins University

NCT04601064

ACTIVE NOT RECRUITING NA 220 participants

A Hybrid Effectiveness Implementation Study of Latino/a Alcohol and Drug Users

Boston University Charles River Campus

NCT04771650

COMPLETED NA 1,072 participants

Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents

Johns Hopkins Bloomberg School of Public Health

NCT02904629

COMPLETED Phase 1 442 participants

Acute Intervention to Reduce Distress Following Sexual Assault

Medical University of South Carolina

NCT01622855

COMPLETED NA 354 participants

Multimedia WORTH With Black Drug-Involved Women on Probation

Columbia University

NCT02391233

COMPLETED NA 294 participants

Alcohol Screening in an Ethnically Diverse Sample of Adolescents in Primary Care

RAND

NCT01797835

COMPLETED NA 196 participants

Prevention and Risk: Treatment With a New Emphasis on Relationships

Hunter College of City University of New York

NCT03396367

COMPLETED NA 97 participants

Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions

Treatment Research Institute

NCT02059005

COMPLETED Phase 2 71 participants

Integrated Outpatient Treatment of Opioid Use Disorder and Severe Injection Related Infections

Laura Fanucchi

NCT04677114

COMPLETED NA 65 participants

Intergenerational Strengths-Based Program for American Indian Girls as They Transition to Adulthood

Johns Hopkins Bloomberg School of Public Health

NCT03900312

COMPLETED NA 63 participants

Drug Use and Sexual Risk Behaviors Among Emerging Adults in the ER

University of Michigan

NCT03079856

COMPLETED NA 50 participants

Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention

University of Michigan

NCT03855410

COMPLETED NA 49 participants

Testing the Effectiveness of a Graphic Novel Health Education Curriculum for Patients With Addiction

Treatment Research Institute

NCT02378181

COMPLETED NA 39 participants

Technology-Enhanced Peer Navigation to Improve IDUs' Engagement in HIV Care

Johns Hopkins Bloomberg School of Public Health

NCT01941108

COMPLETED NA 39 participants

HCV Seek, Test and Rapid Treatment for Young PWID

Weill Medical College of Cornell University

NCT03627546

COMPLETED NA 27 participants

Y2Prevent: Preventing Drug Use and HIV Through Empowerment, Social Support and Mentorship (Y2P)

Children's Hospital Los Angeles

NCT04504981

COMPLETED Phase 4 27 participants

Implementation of Onsite, Rapid ART Initiation Among People Who Inject Drugs Living With HIV at Syringe Services Program

University of Miami

NCT04650269

COMPLETED NA 21 participants

Interventions to Improve the HIV PrEP Cascade Among Methamphetamine Users

University of Washington

NCT03584282

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 2
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Drug Use Trial Landscape

26 indexed Drug Use studies · 7 recruiting (27%).

Phase mix: 1 late (III/IV) vs 3 early (I/II).

Top sponsor: University of Michigan (4 trials), 9 others listed. 26 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Drug Use?

PlainTrial tracks 26 US clinical trials for Drug Use, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Drug Use?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.