Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04677114 · ClinicalTrials.gov registry record · Phase 2

Integrated Outpatient Treatment of Opioid Use Disorder and Severe Injection Related Infections

A Phase 2 study of Opioid Use Disorder and Drug Use, sponsored by Laura Fanucchi.

Completed
Registry status
Phase 2
Development phase
71
Enrollment target
1
Study location

NCT04677114: Completed Phase 2 study of Opioid Use Disorder and Drug Use, sponsored by Laura Fanucchi.

NCT04677114 is a Phase 2 study of Opioid Use Disorder and Drug Use that has completed, run by Laura Fanucchi. The registered enrollment target is 71 participants, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04677114, a Phase 2 study of Opioid Use Disorder and Drug Use, has completed, sponsored by Laura Fanucchi.

COMPLETED
Registry status
Phase 2
Development phase
71 participants
Enrollment target
1
Study location

Study Summary

This study will assess the efficacy of an integrated outpatient treatment model for persons with opioid use disorder and injection related infections. The investigators hypothesize that outpatient antibiotic treatment coupled with comprehensive treatment for opioid use disorder will demonstrate a safe and effective way to manage patients. Results could improve the current protocols for the treatment of individuals with opioid use disorder and severe infections.

Primary Outcome

Proportion of urine samples with negative urine drug screen for illicit opioid use

Interventions

  • DRUG Buprenorphine and Outpatient Parenteral Antibiotic Therapy
  • DRUG Buprenorphine and standard of care antibiotic treatment

Study Locations (1)

Kentucky

  • University of Kentucky - Lexington

Trial Details

FieldValue
Enrollment Target 71 participants
Start Date 2021-03-16
Est. Completion 2025-03-06
Phase Phase 2
Laura Fanucchi

2 total trials

What the finished NCT04677114 record still lists

NCT04677114 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 71 participants, a relatively small participant target, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (98% lower).

The record links to 2 conditions, with Opioid Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Buprenorphine and Outpatient Parenteral Antibiotic Therapy is the first listed.

NCT04677114 reports a single indexed study location in Kentucky.

Frequently Asked Questions

What is clinical trial NCT04677114 about?

NCT04677114 is a clinical study titled "Integrated Outpatient Treatment of Opioid Use Disorder and Severe Injection Related Infections". This study will assess the efficacy of an integrated outpatient treatment model for persons with opioid use disorder and injection related infections. The investigators hypothesize that outpatient antibiotic treatment coupled with comprehensive treatment for opioid use disorder will demonstrate a sa...

What is the current status of trial NCT04677114?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 71 participants. The study started on 2021-03-16. Estimated completion is 2025-03-06.

What conditions does trial NCT04677114 study?

This clinical trial studies the following conditions: Opioid Use Disorder, Drug Use.

What interventions are being tested in trial NCT04677114?

The interventions under investigation include: Buprenorphine and Outpatient Parenteral Antibiotic Therapy (DRUG), Buprenorphine and standard of care antibiotic treatment (DRUG).

Who is sponsoring clinical trial NCT04677114?

This trial is sponsored by Laura Fanucchi, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04677114 being conducted?

This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Opioid Use Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04677114's enrollment target sits among peer trials

71 150th of 257 higher than 108 of 257 other Opioid Use Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Opioid Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT05452889 · 71 participants · Early Phase 1

    PET Image in PAH Patients

  • NCT05766943 · 71 participants · NA

    Reduction of Myopotential Interference With Smart Pass in S-ICD Patients

  • NCT06229678 · 71 participants · Early Phase 1

    Ketones, SGLT2, HFrEF

  • NCT06377566 · 71 participants · Phase 2

    A Study of BV-AVD in People With Bulky Hodgkin Lymphoma

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04677114, the US trial registry maintained by the National Library of Medicine. NCT04677114 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.