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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Diffuse Large B Cell Lymphoma (DLBCL): early-phase trial registry

5 of 11 indexed Diffuse Large B Cell Lymphoma (DLBCL) trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 5 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Diffuse Large B Cell Lymphoma (DLBCL): 11 US clinical trials tracked, 5 recruiting.

Diffuse Large B Cell Lymphoma (DLBCL) is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 3 of these trials.

Enrollment posture brief

Registry condition diffuse-large-b-cell-lymphoma-dlbcl

OPEN 5 | RECR 45% | LATE 2 | EARLY 8 | RANK #1577 | SPON 3

Nearest open-share peer: Advanced Breast Carcinoma (45% recruiting · 11 trials)

Acute Pancreatitis81.8%Acute Stroke45.5%Diffuse Large B Cell Lym (th…45%Acquired Brain Injury36.4%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near Diffuse Large B Cell Lymphoma (DLBCL)

Diffuse Large B Cell Lymphoma (DLBCL) lists 5 open slots (45% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Diffuse Large B Cell Lymphoma (DLBCL) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Diffuse Large B Cell Lymphoma (DLBCL) recruits in line with its size-band peers.

    5 of 11 indexed trials (45.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Diffuse Large B Cell Lymphoma (DLBCL) research.

    Memorial Sloan Kettering Cancer Center accounts for 3 of 11 trials (27.3%). 8 distinct sponsors appear on at least one study for this condition label.

  3. Typical Diffuse Large B Cell Lymphoma (DLBCL) enrolment sits around 115 participants.

    Median target enrolment is 115 among the 11 trials that report a genuine target (sentinel values excluded). 5 of those (45.5%) plan for fewer than 100 participants.

  4. Diffuse Large B Cell Lymphoma (DLBCL) research is mostly interventional.

    11 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 25Phase 32

Open and recent trials

11 total, page 1 of 1

RECRUITING Phase 1 572 participants

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Nurix Therapeutics

NCT05131022

RECRUITING Phase 3 400 participants

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

Lyell Immunopharma

NCT07188558

RECRUITING Phase 1 248 participants

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

Nurix Therapeutics

NCT04830137

RECRUITING Phase 2 42 participants

A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma

Memorial Sloan Kettering Cancer Center

NCT06765317

RECRUITING Phase 2 40 participants

A Study to Evaluate the Impact of Mosunetuzumab Consolidation for Older Patients With Diffuse Large B-cell Lymphoma (DLBCL) Who Have Detectable Amounts of ctDNA (Circulating Tumor DNA) at the End of Treatment With Pola-R-mini-CHP

Danielle Wallace

NCT06828991

ACTIVE NOT RECRUITING Phase 3 904 participants

A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

Regeneron Pharmaceuticals

NCT06091865

ACTIVE NOT RECRUITING NA 201 participants

Comprehensive Geriatric Assessment to Predict Toxic Events in Older Patients With Non-Hodgkin Lymphoma With Imbedded Pilot Study of Pre-Phase Therapy

Memorial Sloan Kettering Cancer Center

NCT01829958

ACTIVE NOT RECRUITING Phase 2 59 participants

Study of the Impact of CD34+ Cell Dose on Absolute Lymphocyte Count Following High-Dose Therapy and Autologous Stem Cell Transplantation for Relapsed and Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Memorial Sloan Kettering Cancer Center

NCT02570542

ACTIVE NOT RECRUITING Phase 2 28 participants

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

Patrick C. Johnson, MD

NCT05583149

COMPLETED Phase 2 115 participants

Study of Efficacy and Safety of CTL019 in Adult DLBCL Patients

Novartis Pharmaceuticals

NCT02445248

COMPLETED Phase 1 18 participants

CLBR001 and SWI019 in Patients With Relapsed / Refractory B-cell Malignancies

Calibr, a division of Scripps Research

NCT04450069

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 5
Phase 3 2

Named interventions

Most-linked intervention names on Diffuse Large B Cell Lymphoma (DLBCL) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Lymphodepleting chemotherapy Drug
2 trials
Rituximab Drug
2 trials
Doxorubicin Drug
2 trials
Cyclophosphamide Drug
2 trials
CLBR001 and SWI019 Combination
1 trials
Autologous Stem Cell Transplantation Procedure
1 trials
carmustine, etoposide, cytarabine, melphalan Drug
1 trials
Lisocabtagene Maraleucel Drug
1 trials

US sites by state

Facility locations filed on Diffuse Large B Cell Lymphoma (DLBCL) trials. A trial with sites in several states counts in each.

New York 9 trials
Texas 6 trials
California 6 trials
Illinois 5 trials
Ohio 4 trials
New Jersey 4 trials
Wisconsin 3 trials
Utah 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Diffuse Large B Cell Lymphoma (DLBCL) page

11 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diffuse Large B Cell Lymphoma (DLBCL) condition card totals 11 registered trials; most-linked intervention Lymphodepleting chemotherapy; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.