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NCT02570542 · ClinicalTrials.gov registry record · Phase 2

Study of the Impact of CD34+ Cell Dose on Absolute Lymphocyte Count Following High-Dose Therapy and Autologous Stem Cell Transplantation for Relapsed and Refractory Diffuse Large B-cell Lymphoma (DLBCL)

A Phase 2 study of Diffuse Large B Cell Lymphoma (DLBCL) and Refractory Diffuse Large B Cell Lymphoma (DLBCL), sponsored by Memorial Sloan Kettering Cancer Center.

Active
Registry status
Phase 2
Development phase
59
Enrollment target
14
Study locations

NCT02570542 is a Phase 2 study of Diffuse Large B Cell Lymphoma (DLBCL) and Refractory Diffuse Large B Cell Lymphoma (DLBCL) that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 59 participants, below the 257-participant average among 10 other Diffuse Large B Cell Lymphoma (DLBCL) trials with a reported enrollment target (77% lower). The trial reports 14 study locations across 6 states.

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The verdict

NCT02570542, a Phase 2 study of Diffuse Large B Cell Lymphoma (DLBCL) and Refractory Diffuse Large B Cell Lymphoma (DLBCL), is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
59 participants
Enrollment target
14
Study locations

Study Summary

The purpose of this study is to study the impact of stem cell dose on outcome after autologous transplant.

Interventions

  • DRUG Plerixafor
  • PROCEDURE leukapheresis
  • DRUG carmustine, etoposide, cytarabine, melphalan
  • PROCEDURE Autologous Stem Cell Transplantation

Study Locations (14)

New York

  • Memorial Sloan Kettering Commack (Consent and Follow-up Only) - Commack
  • Memorial Sloan Kettering Westchester - Harrison
  • Northwell Health (Data collection only) - Manhasset
  • Memorial Sloan Kettering Cancer Center - New York
  • Columbia University - New York
  • University of Rochester Medical Center - Rochester
  • Memorial Sloan Kettering Nassau (Consent and Follow up Only) - Uniondale

New Jersey

  • Memorial Sloan Kettering Basking Ridge (Consent and Follow-Up Only) - Basking Ridge
  • Memorial Sloan Kettering Monmouth (Consent and Follow up Only) - Middletown
  • Memorial Sloan Kettering Bergen (Consent and Follow Up Only) - Montvale

Nebraska

  • University of Nebraska Medical Center - Omaha

Tennessee

  • Tennessee Oncology - Nashville

Texas

  • Texas Transplant Institute - San Antonio

Wisconsin

  • Medical College of Wisconsin - Milwaukee

Trial Details

FieldValue
Enrollment Target 59 participants
Start Date 2015-10
Est. Completion 2026-10
Phase Phase 2

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT02570542

The ClinicalTrials.gov registry entry for NCT02570542 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 59 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 257-participant average among 10 other Diffuse Large B Cell Lymphoma (DLBCL) trials with a reported enrollment target (77% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Diffuse Large B Cell Lymphoma (DLBCL) appearing as the primary indexed condition, and to 4 interventions - of which Plerixafor is the first listed.

NCT02570542 reports 14 study locations spanning 6 distinct geographic areas - top geographies include New York, New Jersey, Nebraska.

Frequently Asked Questions

What is clinical trial NCT02570542 about?

NCT02570542 is a clinical study titled "Study of the Impact of CD34+ Cell Dose on Absolute Lymphocyte Count Following High-Dose Therapy and Autologous Stem Cell Transplantation for Relapsed and Refractory Diffuse Large B-cell Lymphoma (DLBCL)". The purpose of this study is to study the impact of stem cell dose on outcome after autologous transplant.

What is the current status of trial NCT02570542?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 59 participants. The study started on 2015-10. Estimated completion is 2026-10.

What conditions does trial NCT02570542 study?

This clinical trial studies the following conditions: Diffuse Large B Cell Lymphoma (DLBCL), Refractory Diffuse Large B Cell Lymphoma (DLBCL), Relapsed Diffuse Large B-cell Lymphoma (DLBCL).

What interventions are being tested in trial NCT02570542?

The interventions under investigation include: Plerixafor (DRUG), leukapheresis (PROCEDURE), carmustine, etoposide, cytarabine, melphalan (DRUG), Autologous Stem Cell Transplantation (PROCEDURE).

Who is sponsoring clinical trial NCT02570542?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02570542 being conducted?

This trial has 14 study locations across Nebraska, New Jersey, New York, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Diffuse Large B Cell Lymphoma (DLBCL)

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.