Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Diastolic Heart Failure: early-phase trial registry
4 of 8 indexed Diastolic Heart Failure trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 4 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Diastolic Heart Failure: 8 US clinical trials tracked, 4 recruiting.
Diastolic Heart Failure is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Electrophysiology Research Foundation, running 1 of these trials.
Enrollment posture brief
Registry condition diastolic-heart-failure
OPEN 4 | RECR 50% | LATE 2 | EARLY 4 | RANK #2176 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
Diastolic Heart Failure lists 4 open slots (50% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Diastolic Heart Failure on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Diastolic Heart Failure is recruiting above its size-band peers.
4 of 8 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Diastolic Heart Failure trials is spread across many organizations.
Electrophysiology Research Foundation accounts for 1 of 8 trials (12.5%). 8 distinct sponsors appear on at least one study for this condition label.
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Typical Diastolic Heart Failure enrolment sits around 200 participants.
Median target enrolment is 200 among the 8 trials that report a genuine target (sentinel values excluded). 3 of those (37.5%) plan for fewer than 100 participants.
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Diastolic Heart Failure research is mostly interventional.
7 interventional and 1 observational studies make up this index (87.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Assessment of CCM in HF With Higher Ejection Fraction
Impulse Dynamics
NCT05064709
Purinergic Signaling and the Postmenopausal Heart
Beth Israel Deaconess Medical Center
NCT06015776
Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure
Electrophysiology Research Foundation
NCT04160000
Prevention of Age-associated Cardiac and Vascular Dysfunction Using Avmacol ES
Texas Tech University Health Sciences Center
NCT05408559
A Study of the Effectiveness of Sitaxsentan Sodium in Patients With Diastolic Heart Failure
Pfizer
NCT00303498
PIE II: Pharmacological Intervention in the Elderly II
Wake Forest University
NCT00123955
Physiological Effects of Grape Seed Extract in Diastolic Heart Failure
University of Michigan
NCT01185067
Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEF
University of Pennsylvania
NCT02256345
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 2 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Diastolic Heart Failure records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Diastolic Heart Failure trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Diastolic Heart Failure page
8 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Diastolic Heart Failure trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Electrophysiology Research Foundation sponsors the most Diastolic Heart Failure trials on record, review their full trial history before evaluating a specific study. See Electrophysiology Research Foundation's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diastolic Heart Failure condition card totals 8 registered trials; most-linked intervention Placebo; top US site state Arizona. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.