Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Diarrhea: early-phase trial registry
7 of 25 indexed Diarrhea trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #652 of 28,707 conditions by registered trial count.
25 US clinical trials · 7 currently recruiting · #652 of 28,707 conditions by registered trial count
Diarrhea: 25 US clinical trials tracked, 7 recruiting.
Diarrhea is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Bausch Health Americas, running 2 of these trials.
Enrollment posture brief
Registry condition diarrhea
OPEN 7 | RECR 28% | LATE 3 | EARLY 15 | RANK #652 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Pain (28% recruiting · 377 trials)
Diarrhea lists 7 open slots (28% of 25 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Diarrhea on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Diarrhea is recruiting below its size-band peers.
7 of 25 indexed trials (28%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Diarrhea trials is spread across many organizations.
Bausch Health Americas accounts for 2 of 25 trials (8%). 23 distinct sponsors appear on at least one study for this condition label.
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Most Diarrhea trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 25 trials that report a genuine target (sentinel values excluded). 17 of those (68%) plan for fewer than 100 participants.
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Diarrhea research is mostly interventional.
23 interventional and 2 observational studies make up this index (92% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
25 total, page 1 of 1
First in Human Dose Escalation Study Evaluating the Safety and Immunogenicity of IVT's Shigella-04 Vaccine in Healthy Young Adults
Inventprise
NCT07205926
Rifaximin 200 mg Plus Oral Rehydration vs Oral Rehydration Alone in Children With Acute Diarrhea
Bausch Health Americas
NCT07285785
Fecal Microbiota Transplantation for IBS
Madhusudan (Madhu) Grover, MBBS
NCT05776914
Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients
M.D. Anderson Cancer Center
NCT04038619
GI Alpha-Gal Study
University of North Carolina, Chapel Hill
NCT06268717
Novel Pilot Study to Treat Symptoms of IBS With Diarrhea Using Combination Therapy of a Low-FODMAP Diet and a Neuromodulator
Mayo Clinic
NCT06684470
A Study of SER-155 to Treat Diarrhea in People on Immunotherapy
Memorial Sloan Kettering Cancer Center
NCT06801067
Wells and Enteric Disease Transmission
Temple University
NCT04826991
Microbiota Transplant Therapy for Children With Both Autism Spectrum Disorder and Gastrointestinal Disorders
Gut-Brain-Axis Therapeutics
NCT06503978
MTT for Children With ASD Who Have Gastrointestinal Disorders
Arizona State University
NCT04182633
A Trial of Tap Water Treatment in the Elderly
National Institute on Aging (NIA)
NCT00058942
Genetic Trial to Study Diarrhea in Patients With Stage III Colon Cancer Who Are Receiving Chemotherapy
Alliance for Clinical Trials in Oncology
NCT00048971
Development and Validation of the Automated Evaluation of Gastrointestinal Symptoms (AEGIS) Platform
Cedars-Sinai Medical Center
NCT02436057
A Study of Crofelemer to Treat Diarrhea Irritable Bowel Syndrome
Bausch Health Americas
NCT00101725
Study of CB-183,315 in Participants With Clostridium Difficile Infection
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT01085591
ETEC Logistics Trial (TREK)
Intercell USA
NCT00516659
Yogurt Study in Children 2-4 Years Old Attending Daycare
Georgetown University
NCT00760851
Clinical Study to Assess the Efficacy of IMM-124E (Travelan®) in a Controlled Human Infection Model
Immuron
NCT05933525
Dose Escalating Study of Intramuscular Invaplex[AR-DETOX]
PATH
NCT03869333
Examining the Effect of Ondansetron on Bowel Prep Success
State University of New York - Downstate Medical Center
NCT05439772
Invaplex 50 Vaccine Dose-Ranging
U.S. Army Medical Research and Development Command
NCT00082069
AcuGraph and Digestive Symptoms
Logan College of Chiropractic
NCT00846794
A Study of Colesevelam for Lenalidomide-Associated Diarrhea
Memorial Sloan Kettering Cancer Center
NCT03767257
Probiotic Yogurt Supplement in Reducing Diarrhea in Patients With Metastatic Kidney Cancer Being Treated With Vascular Endothelial Growth Factor-Tyrosine Kinase Inhibitor
City of Hope Medical Center
NCT02944617
Irinotecan and Celecoxib in Treating Patients With Unresectable or Metastatic Colorectal Cancer
Roswell Park Cancer Institute
NCT00084721
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 8 |
| Phase 3 | 1 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Diarrhea records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Diarrhea trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Diarrhea page
25 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 7 Diarrhea trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Bausch Health Americas sponsors the most Diarrhea trials on record, review their full trial history before evaluating a specific study. See Bausch Health Americas's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diarrhea condition card totals 25 registered trials; most-linked intervention Placebo; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.