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NCT04826991 · ClinicalTrials.gov registry record · NA
Wells and Enteric Disease Transmission
A NA study of Diarrhea and Respiratory Viral Infection, sponsored by Temple University.
- Active
- Registry status
- NA
- Development phase
- 908
- Enrollment target
- 1
- Study location
NCT04826991: Active NA study of Diarrhea and Respiratory Viral Infection, sponsored by Temple University.
NCT04826991 is a NA study of Diarrhea and Respiratory Viral Infection that is active but no longer recruiting, run by Temple University. The registered enrollment target is 908 participants, above the 119-participant average among 24 other Diarrhea trials with a reported enrollment target (663% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04826991, a NA study of Diarrhea and Respiratory Viral Infection, is active but no longer recruiting, sponsored by Temple University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 908 participants
- Enrollment target
- 1
- Study location
Study Summary
Approximately 40 million people in the US are served by private, and frequently untreated, wells. Our best estimate is that 1.3 million cases of gastrointestinal illnesses (GI) per year are attributed to consuming water from untreated private wells in the US, but in reality, there are no robust epidemiological data that can be used to estimate cases of GI attributable to these sources. We propose the first randomized controlled trial (RCT) to estimate the burden of GI associated with private well water. We will test if household treatment of private well water by ultraviolet light (UV) vs. sham (inactive UV device) decreases the incidence of GI in children under 5. We will also examine the presence of viral, bacterial, and protozoan pathogens in stool and well water from participants. These data will fill a knowledge gap on sporadic GI associated with federally-unregulated private water supplies in the US.
Primary Outcome
The investigators will collect data on the presence of gastrointestinal illness symptoms through weekly text messages. Households that report symptoms through text messages will be directed to an online illness questionnaire to characterize the symptoms (type, incidence, severity, duration, etc.), as well as relevant exposure information such as recent travel, exposure to ill persons, etc. Incident gastrointestinal illness (GI) is defined by the reporting of a minimum of three episodes of diarrh
Conditions Studied
Interventions
- DEVICE Active UV Device
- DEVICE Inactive UV Device
Study Locations (1)
Pennsylvania
- Temple University - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 908 participants |
| Start Date | 2021-07-01 |
| Est. Completion | 2027-08-31 |
| Phase | NA |
What the registry record for NCT04826991 still lists
NCT04826991 is an interventional study that assigns participants to a tested intervention. The registered 908 participants enrollment target is mid-sized for trials with a published cap, above the 119-participant average among 24 other Diarrhea trials with a reported enrollment target (663% higher).
The record links to 4 conditions, with Diarrhea appearing as the primary indexed condition, and to 2 interventions - of which Active UV Device is the first listed.
NCT04826991 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT04826991 about?
NCT04826991 is a clinical study titled "Wells and Enteric Disease Transmission". Approximately 40 million people in the US are served by private, and frequently untreated, wells. Our best estimate is that 1.3 million cases of gastrointestinal illnesses (GI) per year are attributed to consuming water from untreated private wells in the US, but in reality, there are no robust epid...
What is the current status of trial NCT04826991?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 908 participants. The study started on 2021-07-01. Estimated completion is 2027-08-31.
What conditions does trial NCT04826991 study?
This clinical trial studies the following conditions: Diarrhea, Respiratory Viral Infection, Gastrointestinal Infection, Waterborne Diseases.
What interventions are being tested in trial NCT04826991?
The interventions under investigation include: Active UV Device (DEVICE), Inactive UV Device (DEVICE).
Who is sponsoring clinical trial NCT04826991?
This trial is sponsored by Temple University, which has 163 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04826991 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04826991's enrollment target sits among peer trials
908 1st of 24 higher than 24 of 24 other Diarrhea trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Diarrhea trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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