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NCT00001836 · ClinicalTrials.gov registry record

Detection of Coronary Artery Calcification: Comparison of Volumetric and Electron Beam Computed Tomography

A clinical trial of Coronary Disease, sponsored by National Institutes of Health Clinical Center (CC).

Completed
Registry status
213
Enrollment target
1
Study location

NCT00001836: Completed study of Coronary Disease, sponsored by National Institutes of Health Clinical Center (CC).

NCT00001836 is a study of Coronary Disease that has completed, run by National Institutes of Health Clinical Center (CC). The registered enrollment target is 213 participants, below the 2,013-participant average among 34 other Coronary Disease trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00001836, a study of Coronary Disease, has completed, sponsored by National Institutes of Health Clinical Center (CC).

COMPLETED
Registry status
213 participants
Enrollment target
1
Study location

Study Summary

Electron beam computed tomography (EBCT) has been regarded as the state-of-the-art investigation for detecting and quantitating coronary artery calcification. However, EBCT is expensive, and the asymmetric gantry geometry makes it less useful for routine scanning; thus, EBCT is not readily available to the general population. Recent reports have shown that "volumetric" (also known as "helical" or "spiral") scanners, which are much more commonly available than EBCT, can detect coronary artery calcifications. Updated software available to the NIH which will allow for EKG gating of volumetric scans should improve the quality of the images, and thus improve the ability to accurately quantitate coronary calcification by volumetric scanners. We would like to compare the results of volumetric scans with that of standard EBCT in order to characterize similarities and differences between the two scanning techniques. We propose to obtain EBCT and volumetric CT scans of the coronary arteries in a group of patients with known or suspected coronary artery disease and to calculate the calcium score by each method. Our primary analysis will be a comparison of the sensitivities of the two methods.

Conditions Studied

Study Locations (1)

Maryland

  • Warren G. Magnuson Clinical Center (CC) - Bethesda

Trial Details

FieldValue
Enrollment Target 213 participants
Start Date 1998-10
Est. Completion 2001-11

What the finished NCT00001836 record still lists

NCT00001836 is an observational study that tracks outcomes without assigning an intervention. The registered 213 participants enrollment target is mid-sized for trials with a published cap, below the 2,013-participant average among 34 other Coronary Disease trials with a reported enrollment target (89% lower).

The record links to 1 condition, with Coronary Disease appearing as the primary indexed condition, and to 0 interventions.

NCT00001836 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT00001836 about?

NCT00001836 is a clinical study titled "Detection of Coronary Artery Calcification: Comparison of Volumetric and Electron Beam Computed Tomography". Electron beam computed tomography (EBCT) has been regarded as the state-of-the-art investigation for detecting and quantitating coronary artery calcification. However, EBCT is expensive, and the asymmetric gantry geometry makes it less useful for routine scanning; thus, EBCT is not readily available...

What is the current status of trial NCT00001836?

This trial is currently completed. The enrollment target is 213 participants. The study started on 1998-10. Estimated completion is 2001-11.

What conditions does trial NCT00001836 study?

This clinical trial studies the following conditions: Coronary Disease.

Who is sponsoring clinical trial NCT00001836?

This trial is sponsored by National Institutes of Health Clinical Center (CC), which has 338 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00001836 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Coronary Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00001836's enrollment target sits among peer trials

213 23rd of 34 higher than 12 of 34 other Coronary Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Coronary Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00001836, the US trial registry maintained by the National Library of Medicine. NCT00001836 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.