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NCT02100722 · ClinicalTrials.gov registry record · NA

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease

A NA study of Coronary Disease and Coronary Stenosis, sponsored by Stanford University.

Completed
Registry status
NA
Development phase
1,500
Enrollment target
20
Study locations

NCT02100722: Completed NA study of Coronary Disease and Coronary Stenosis, sponsored by Stanford University.

NCT02100722 is a NA study of Coronary Disease and Coronary Stenosis that has completed, run by Stanford University. The registered enrollment target is 1,500 participants, below the 1,975-participant average among 34 other Coronary Disease trials with a reported enrollment target (24% lower). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02100722, a NA study of Coronary Disease and Coronary Stenosis, has completed, sponsored by Stanford University.

COMPLETED
Registry status
NA
Development phase
1,500 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to determine whether Fractional flow reserve (FFR, (coronary pressure wire-based index for assessing the ischemic potential of a coronary lesion)-guided percutaneous coronary intervention (PCI) in patients with multivessel coronary artery disease (CAD) will result in similar outcomes to coronary artery bypass graft surgery (CABG).

Primary Outcome

Death, MI, stroke and any repeat revascularization (MACCE) will be evaluated at 1 year, where subjects contribute data from time of randomization until the occurrence of MACCE or one year follow-up, whichever occurs first. Subjects who die or are lost to follow up before 1 year will be censored at their last recorded activity.

Conditions Studied

Coronary Disease Coronary Stenosis

Interventions

  • PROCEDURE CABG
  • PROCEDURE FFR guided PCI
  • DEVICE Resolute Integrity Stent
  • DEVICE Resolute Onyx Stent

Study Locations (20)

Other

  • Peninsula Health - Frankston
  • St. Vincent's Hospital Melbourne - Melbourne
  • Concord Hospital - Sydney
  • Royal North Shore - Sydney
  • University of Sydney - Sydney
  • Cardiovascular Center Aalst - Aalst
  • Le'Centre Hospitalier de l'Universite de Montreal - Montreal

California

  • Palo Alto VA - Palo Alto
  • Stanford University - Stanford

Kentucky

  • Lexinton VA - Lexington
  • University of Kentucky Medical Center - Lexington

Georgia

  • Atlanta VA Medical Center - Decatur

Illinois

  • Jesse Brown VA Medical Center - Chicago

Kansas

  • University of Kansas Medical Center - Lawrence

Massachusetts

  • Baystate Medical Center - Springfield

Minnesota

  • HealthEast St. Joseph's Hospital - Saint Paul

Trial Details

FieldValue
Enrollment Target 1,500 participants
Start Date 2014-08-25
Est. Completion 2024-12-01
Phase NA
Stanford University

1,744 total trials

What the finished NCT02100722 record still lists

NCT02100722 is an interventional study that assigns participants to a tested intervention. Its 1,500 participants enrollment target places it among the larger protocols in the corpus, below the 1,975-participant average among 34 other Coronary Disease trials with a reported enrollment target (24% lower).

The record links to 2 conditions, with Coronary Disease appearing as the primary indexed condition, and to 4 interventions - of which CABG is the first listed.

NCT02100722 names 20 study sites across 12 states, led by Other, California, Kentucky.

Frequently Asked Questions

What is clinical trial NCT02100722 about?

NCT02100722 is a clinical study titled "A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease". The purpose of this study is to determine whether Fractional flow reserve (FFR, (coronary pressure wire-based index for assessing the ischemic potential of a coronary lesion)-guided percutaneous coronary intervention (PCI) in patients with multivessel coronary artery disease (CAD) will result in sim...

What is the current status of trial NCT02100722?

This trial is currently completed. It is a NA study. The enrollment target is 1,500 participants. The study started on 2014-08-25. Estimated completion is 2024-12-01.

What conditions does trial NCT02100722 study?

This clinical trial studies the following conditions: Coronary Disease, Coronary Stenosis.

What interventions are being tested in trial NCT02100722?

The interventions under investigation include: CABG (PROCEDURE), FFR guided PCI (PROCEDURE), Resolute Integrity Stent (DEVICE), Resolute Onyx Stent (DEVICE).

Who is sponsoring clinical trial NCT02100722?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02100722 being conducted?

This trial has 20 study locations across California, Georgia, Illinois, Kansas, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Coronary Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02100722's enrollment target sits among peer trials

1,500 11th of 34 higher than 24 of 34 other Coronary Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Coronary Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT02100722, the US trial registry maintained by the National Library of Medicine. NCT02100722 (large enrollment · wide site footprint · completed) retrieved and formatted by PlainTrial, see methodology.