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ClinicalTrials.gov 8 recruiting now early-phase tilt small index

Clinical Stage III Gastric Cancer AJCC v8: early-phase trial registry

8 of 16 indexed Clinical Stage III Gastric Cancer AJCC v8 trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,060 of 28,707 conditions by registered trial count.

16 US clinical trials · 8 currently recruiting · #1,060 of 28,707 conditions by registered trial count

Clinical Stage III Gastric Cancer AJCC v8: 16 US clinical trials tracked, 8 recruiting.

Clinical Stage III Gastric Cancer AJCC v8 is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 6 of these trials.

Enrollment posture brief

Registry condition clinical-stage-iii-gastric-cancer-ajcc-v8

OPEN 8 | RECR 50% | LATE 1 | EARLY 13 | RANK #1060 | SPON 6

Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)

Adolescent62.5%Alcohol Intoxication56.3%Clinical Stage III Gastr (this)Clinical Stage III Gastr (th…50%AL Amyloidosis43.8%Allergy18.8%
Open-enrollment share among volume-matched conditions near Clinical Stage III Gastric Cancer AJCC v8

Clinical Stage III Gastric Cancer AJCC v8 lists 8 open slots (50% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Clinical Stage III Gastric Cancer AJCC v8 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Clinical Stage III Gastric Cancer AJCC v8 is recruiting above its size-band peers.

    8 of 16 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Clinical Stage III Gastric Cancer AJCC v8 research.

    National Cancer Institute (NCI) accounts for 6 of 16 trials (37.5%). 8 distinct sponsors appear on at least one study for this condition label.

  3. Most Clinical Stage III Gastric Cancer AJCC v8 trials plan to enrol fewer than 100 people.

    Median target enrolment is 48 among the 16 trials that report a genuine target (sentinel values excluded). 11 of those (68.8%) plan for fewer than 100 participants.

  4. Clinical Stage III Gastric Cancer AJCC v8 research is mostly interventional.

    15 interventional and 1 observational studies make up this index (93.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 26Phase 31

Open and recent trials

16 total, page 1 of 1

RECRUITING Phase 3 382 participants

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Alliance for Clinical Trials in Oncology

NCT05677490

RECRUITING Phase 2 224 participants

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

National Cancer Institute (NCI)

NCT06203600

RECRUITING Phase 1 132 participants

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Mayo Clinic

NCT05269381

RECRUITING Phase 2 116 participants

Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer

Academic and Community Cancer Research United

NCT04660760

RECRUITING NA 66 participants

Feasibility of Auricular Acupressure for Appetite and Weight in Patients With Stage II-IV Gastric, Esophageal, and Pancreatic Cancer

University of Washington

NCT05911243

RECRUITING Phase 1 48 participants

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors

National Cancer Institute (NCI)

NCT06364410

RECRUITING Phase 2 36 participants

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

National Cancer Institute (NCI)

NCT04550494

RECRUITING Early Phase 1 15 participants

Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma

M.D. Anderson Cancer Center

NCT05041153

ACTIVE NOT RECRUITING Phase 2 240 participants

Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer

National Cancer Institute (NCI)

NCT05836584

ACTIVE NOT RECRUITING 52 participants

Early Recovery After Surgery Protocol in Improving Quality of Life in Participants With Stage 0-IIIC Gastric Cancer Undergoing Surgery

City of Hope Medical Center

NCT03997162

ACTIVE NOT RECRUITING Phase 2 48 participants

A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma

Thomas Jefferson University

NCT04111172

ACTIVE NOT RECRUITING Phase 1 36 participants

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

Mayo Clinic

NCT04007744

ACTIVE NOT RECRUITING Phase 1 25 participants

Short-Course Chemoradiotherapy Followed by Chemotherapy for the Treatment of Resectable Gastric Adenocarcinoma

M.D. Anderson Cancer Center

NCT04523818

ACTIVE NOT RECRUITING Phase 2 17 participants

Berzosertib and Irinotecan in Treating Patients With Progressive, Metastatic, or Unresectable TP53 Mutant Gastric or Gastroesophageal Junction Cancer

National Cancer Institute (NCI)

NCT03641313

ACTIVE NOT RECRUITING Phase 1 10 participants

Testing the Addition of an Anticancer Drug, BAY 1895344, to the Usual Chemotherapy With FOLFIRI in Advanced or Metastatic Cancers of the Stomach and Intestines

National Cancer Institute (NCI)

NCT04535401

COMPLETED Early Phase 1 9 participants

Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Adenocarcinoma

M.D. Anderson Cancer Center

NCT03395847

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 6
Phase 3 1

Named interventions

Most-linked intervention names on Clinical Stage III Gastric Cancer AJCC v8 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Biospecimen Collection Procedure
7 trials
Computed Tomography Procedure
4 trials
Pembrolizumab Biological
4 trials
Magnetic Resonance Imaging Procedure
3 trials
Fluorouracil Drug
3 trials
Irinotecan Drug
2 trials
Nivolumab Biological
2 trials
Best Practice Other
2 trials

US sites by state

Facility locations filed on Clinical Stage III Gastric Cancer AJCC v8 trials. A trial with sites in several states counts in each.

California 7 trials
Florida 5 trials
Texas 4 trials
Arizona 3 trials
Pennsylvania 2 trials
Minnesota 2 trials
Maryland 2 trials
Kansas 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Clinical Stage III Gastric Cancer AJCC v8 page

16 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 8 Clinical Stage III Gastric Cancer AJCC v8 trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • National Cancer Institute (NCI) sponsors the most Clinical Stage III Gastric Cancer AJCC v8 trials on record, review their full trial history before evaluating a specific study. See National Cancer Institute (NCI)'s trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Clinical Stage III Gastric Cancer AJCC v8 condition card totals 16 registered trials; most-linked intervention Biospecimen Collection; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.