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ClinicalTrials.gov official registry

Chronic Sinusitis clinical trials

All 10 indexed Chronic Sinusitis trials have closed enrollment.

10 US clinical trials ·

Chronic Sinusitis is the subject of 10 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Entellus Medical, running 2 of these trials.

The research picture

Chronic Sinusitis has 10 registered US clinical trials; none are currently listed as recruiting, so most are completed or in follow-up.

0
recruiting participants now
0%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: Entellus Medical
Phase 23Phase 31

Active & Recent Trials

10 total, page 1 of 1

ACTIVE NOT RECRUITING 1,200 participants

Genetic Factors in Chronic Sinusitis

University of Chicago

NCT00880516

COMPLETED Phase 2 180 participants

Evaluating SPRC-AB01 in Post-Surgical Subjects With Chronic Sinusitis

Naryx Pharma

NCT00447837

COMPLETED NA 151 participants

Randomized Evaluation of Maxillary Antrostomy Versus Ostial Dilation Efficacy Through Long-Term Follow-Up

Entellus Medical

NCT01525849

COMPLETED NA 62 participants

Intraoperative and Post-operative Analgesic Effect of IV Acetaminophen for Sinus Surgery

The University of Texas Health Science Center, Houston

NCT01608308

COMPLETED NA 44 participants

Safety and Efficacy of Balloon Sinuplasty in Pediatric Sinusitis

Integra LifeSciences Corporation

NCT00939471

COMPLETED Phase 2 33 participants

Efficacy of Dupilumab for Patients With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)

Johns Hopkins University

NCT04362501

COMPLETED Phase 2 28 participants

Esmolol vs. Labetalol in Endoscopic Sinus Surgery

The University of Texas Medical Branch, Galveston

NCT03661346

COMPLETED Phase 3 23 participants

Nasal Packing as a Drug Delivery System Postoperatively in Chronic Sinusitis With Polyposis

University of Michigan

NCT01197612

COMPLETED NA 21 participants

XprESS Maxillary Balloon Dilation Study

Entellus Medical

NCT01525862

COMPLETED NA 20 participants

The PIO (Propel In Office) III Study of In-office Placement of a Steroid-Eluting Implant Immediately Following Ethmoid Sinus Surgery

ENT and Allergy Associates

NCT02687438

Phase Distribution

PhaseTrial count
Phase 2 3
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Chronic Sinusitis Trial Landscape

10 indexed Chronic Sinusitis studies · 0 recruiting (0%).

Phase mix: 1 late (III/IV) vs 3 early (I/II).

Top sponsor: Entellus Medical (2 trials), 8 others listed. 10 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Chronic Sinusitis?

PlainTrial tracks 10 US clinical trials for Chronic Sinusitis, of which 0 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Chronic Sinusitis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.