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Chronic Low Back Pain (CLBP) clinical trials
8 of 9 indexed Chronic Low Back Pain (CLBP) trials are currently recruiting.
9 US clinical trials · 8 currently recruiting
Chronic Low Back Pain (CLBP) is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Edward Hines Jr. VA Hospital, running 1 of these trials.
The research picture
Chronic Low Back Pain (CLBP) has 9 registered US clinical trials, 8 of them open to new participants right now, about 89% of the total.
- 8
- recruiting participants now
- 89%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 1
- top sponsor: Edward Hines Jr. VA Hospital
Active & Recent Trials
9 total, page 1 of 1
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain
Eli Lilly and Company
NCT07035093
A Superiority Trial of Radiofrequency Ablation for Low Back Pain
University of Washington
NCT07222462
Resilience Enhancement Following Sleep Treatment
University of Virginia
NCT07298941
Brief Pain Exposure Therapy (BPET) For Nociplastic Pain
University of Michigan
NCT06208514
Treatment Validation for Myofascial Pain
Ajay Wasan, MD, Msc
NCT07133139
A Mediation Analysis Investigating Dry Needling Treatment Mechanisms in a Chronic Low Back Pain Population
University of Florida
NCT06940492
Chronic Low Back Pain and Osteopathic Manipulation Treatment
Edward Hines Jr. VA Hospital
NCT07161661
A Prospective Evaluation of Spinal Cord Induced Muscle Stimulation (MuscleSCS) for the Treatment of Chronic Low Back Pain
Saint Francis Hospital
NCT07215104
Sustained Acoustic Medicine for Chronic Low Back Pain Secondary to Herniated Nucleus Pulposus or Other Conditions
ZetrOZ
NCT02609854
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Chronic Low Back Pain (CLBP) Trial Landscape
9 indexed Chronic Low Back Pain (CLBP) studies · 8 recruiting (89%).
Phase mix: 1 late (III/IV) vs 1 early (I/II).
Top sponsor: Edward Hines Jr. VA Hospital (1 trial), 8 others listed. 9 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Chronic Low Back Pain (CLBP)?
PlainTrial tracks 9 US clinical trials for Chronic Low Back Pain (CLBP), of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Chronic Low Back Pain (CLBP)?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.