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NCT07222462 · ClinicalTrials.gov registry record · NA
A Superiority Trial of Radiofrequency Ablation for Low Back Pain
A NA study of Chronic Low Back Pain (CLBP), sponsored by University of Washington.
- Recruiting
- Registry status
- NA
- Development phase
- 300
- Enrollment target
- 3
- Study locations
NCT07222462: Recruiting NA study of Chronic Low Back Pain (CLBP), sponsored by University of Washington.
NCT07222462 is a NA study of Chronic Low Back Pain (CLBP) that is actively recruiting participants, run by University of Washington. The registered enrollment target is 300 participants, above the 163-participant average among 8 other Chronic Low Back Pain (CLBP) trials with a reported enrollment target (84% higher). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07222462, a NA study of Chronic Low Back Pain (CLBP), is actively recruiting participants, sponsored by University of Washington.
- RECRUITING
- Registry status
- NA
- Development phase
- 300 participants
- Enrollment target
- 3
- Study locations
Study Summary
The purpose of the ASTRAL Study is to evaluate the effectiveness of LRFA (Lumbar radiofrequency ablation) against a control procedure. The ASTRAL Study will enroll individuals with chronic low back pain (CLBP) and randomly assign them to one of three groups: lumbar radiofrequency ablation using conventional electrodes placed parallel to the medial branch nerves (LRFA-C), lumbar radiofrequency ablation using multi-tined electrodes placed perpendicular to the medial branch nerves (LRFA-M), or a simulated radiofrequency ablation procedure.
Primary Outcome
Measured using the Roland-Morris Disability Questionnaire (RMDQ), a 24-item questionnaire that evaluates patients' self-reported functional limitations due to back pain. The total score ranges from 0 (no disability) to 24 (severe disability).
Conditions Studied
Interventions
- PROCEDURE Lumbar radiofrequency ablation with conventional electrodes (LRFA-C)
- PROCEDURE Lumbar radiofrequency ablation with multi-tined electrodes (LRFA-M)
- PROCEDURE Simulated lumbar radiofrequency ablation
Study Locations (3)
Georgia
- Emory Musculoskeletal Institute - Atlanta
Ohio
- Cleveland Clinic - Cleveland
Utah
- University of Utah Orthopaedic Center/PM&R - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2026-02-04 |
| Est. Completion | 2029-08 |
| Phase | NA |
What NCT07222462 shows while recruiting
NCT07222462 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, above the 163-participant average among 8 other Chronic Low Back Pain (CLBP) trials with a reported enrollment target (84% higher).
The record links to 1 condition, with Chronic Low Back Pain (CLBP) appearing as the primary indexed condition, and to 3 interventions - of which Lumbar radiofrequency ablation with conventional electrodes (LRFA-C) is the first listed.
NCT07222462 reports a single indexed study location in Georgia, Ohio, Utah.
Frequently Asked Questions
What is clinical trial NCT07222462 about?
NCT07222462 is a clinical study titled "A Superiority Trial of Radiofrequency Ablation for Low Back Pain". The purpose of the ASTRAL Study is to evaluate the effectiveness of LRFA (Lumbar radiofrequency ablation) against a control procedure. The ASTRAL Study will enroll individuals with chronic low back pain (CLBP) and randomly assign them to one of three groups: lumbar radiofrequency ablation using conv...
What is the current status of trial NCT07222462?
This trial is currently recruiting. It is a NA study. The enrollment target is 300 participants. The study started on 2026-02-04. Estimated completion is 2029-08.
What conditions does trial NCT07222462 study?
This clinical trial studies the following conditions: Chronic Low Back Pain (CLBP).
What interventions are being tested in trial NCT07222462?
The interventions under investigation include: Lumbar radiofrequency ablation with conventional electrodes (LRFA-C) (PROCEDURE), Lumbar radiofrequency ablation with multi-tined electrodes (LRFA-M) (PROCEDURE), Simulated lumbar radiofrequency ablation (PROCEDURE).
Who is sponsoring clinical trial NCT07222462?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07222462 being conducted?
This trial has 3 study locations across Georgia, Ohio, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Low Back Pain (CLBP)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07222462's enrollment target sits among peer trials
300 2nd of 8 higher than 6 of 8 other Chronic Low Back Pain (CLBP) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Low Back Pain (CLBP) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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