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NCT06336655 · ClinicalTrials.gov registry record · Phase 2
Physiology of Unloading VA ECMO Trial
A Phase 2 study of Cardiogenic Shock, sponsored by University of Utah.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 104
- Enrollment target
- 1
- Study location
NCT06336655: Recruiting Phase 2 study of Cardiogenic Shock, sponsored by University of Utah.
NCT06336655 is a Phase 2 study of Cardiogenic Shock that is actively recruiting participants, run by University of Utah. The registered enrollment target is 104 participants, below the 628-participant average among 16 other Cardiogenic Shock trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06336655, a Phase 2 study of Cardiogenic Shock, is actively recruiting participants, sponsored by University of Utah.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 104 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to compare the use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) with and without left ventricular (LV) unloading in patients being treated for cardiogenic shock (CS). The main aims of the study are: 1. To determine the physiologic effects on cardiopulmonary congestion of adding LV unloading to VA ECMO 2. To determine the effects on myocardial function of adding LV unloading to ECMO 3. To test the effects on myocardial recovery of adding LV unloading to VA ECMO Participants who are being treated with VA ECMO will be randomized to receive or not receive LV unloading in the form of an intra-aortic balloon pump (IABP). Over the course of the study, the investigators will obtain measurements via lab work, echocardiography, and pulmonary artery catheter that will allow comparison of the two groups.
Primary Outcome
Change in pulmonary capillary wedge pressure (PCWP) from ECMO start to ECMO day 5 (Day 5 - Baseline) with and without LV unloading
Conditions Studied
Interventions
- DEVICE IABP
Study Locations (1)
Utah
- University of Utah - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 104 participants |
| Start Date | 2024-10-02 |
| Est. Completion | 2029-02-01 |
| Phase | Phase 2 |
What NCT06336655 shows while recruiting
NCT06336655 is an interventional study that assigns participants to a tested intervention. The registered 104 participants enrollment target is mid-sized for trials with a published cap, below the 628-participant average among 16 other Cardiogenic Shock trials with a reported enrollment target (83% lower).
The record links to 1 condition, with Cardiogenic Shock appearing as the primary indexed condition, and to 1 intervention - of which IABP is the first listed.
NCT06336655 reports a single indexed study location in Utah.
Frequently Asked Questions
What is clinical trial NCT06336655 about?
NCT06336655 is a clinical study titled "Physiology of Unloading VA ECMO Trial". The goal of this clinical trial is to compare the use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) with and without left ventricular (LV) unloading in patients being treated for cardiogenic shock (CS). The main aims of the study are: 1. To determine the physiologic effects on card...
What is the current status of trial NCT06336655?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 104 participants. The study started on 2024-10-02. Estimated completion is 2029-02-01.
What conditions does trial NCT06336655 study?
This clinical trial studies the following conditions: Cardiogenic Shock.
What interventions are being tested in trial NCT06336655?
The interventions under investigation include: IABP (DEVICE).
Who is sponsoring clinical trial NCT06336655?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06336655 being conducted?
This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiogenic Shock
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06336655's enrollment target sits among peer trials
104 9th of 16 higher than 8 of 16 other Cardiogenic Shock trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiogenic Shock trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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