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ClinicalTrials.gov 6 recruiting now early-phase tilt small index

Borderline Personality Disorder: early-phase trial registry

6 of 17 indexed Borderline Personality Disorder trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,004 of 28,707 conditions by registered trial count.

17 US clinical trials · 6 currently recruiting · #1,004 of 28,707 conditions by registered trial count

Borderline Personality Disorder: 17 US clinical trials tracked, 6 recruiting.

Borderline Personality Disorder is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Yale University, running 3 of these trials.

Enrollment posture brief

Registry condition borderline-personality-disorder

OPEN 6 | RECR 35% | LATE 0 | EARLY 5 | RANK #1004 | SPON 3

Nearest open-share peer: Arrhythmia (35% recruiting · 17 trials)

Acute Myeloid Leukemia, in R70.6%Abdominal Aortic Aneurysm52.9%Borderline Personality D (th…35%Acute Lymphoblastic Leukemia23.5%Actinic Keratosis11.8%
Open-enrollment share among volume-matched conditions near Borderline Personality Disorder

Borderline Personality Disorder lists 6 open slots (35% of 17 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Borderline Personality Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Borderline Personality Disorder is recruiting below its size-band peers.

    6 of 17 indexed trials (35.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Borderline Personality Disorder research.

    Yale University accounts for 3 of 17 trials (17.6%). 13 distinct sponsors appear on at least one study for this condition label.

  3. Most Borderline Personality Disorder trials plan to enrol fewer than 100 people.

    Median target enrolment is 61 among the 17 trials that report a genuine target (sentinel values excluded). 12 of those (70.6%) plan for fewer than 100 participants.

  4. Borderline Personality Disorder research is mostly interventional.

    16 interventional and 1 observational studies make up this index (94.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 24

Open and recent trials

17 total, page 1 of 1

RECRUITING NA 600 participants

Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

Massachusetts General Hospital

NCT04296604

RECRUITING Phase 2 150 participants

Mindfulness-based Neurofeedback to Augment Psychotherapy for Adults With Borderline Personality Disorder

Yale University

NCT06446765

RECRUITING NA 130 participants

Cognitive Reappraisal Training for Borderline Personality (BPD)

Icahn School of Medicine at Mount Sinai

NCT06772831

RECRUITING NA 80 participants

Circuit-Based Approach to Suicide: Biomarkers, Predictors, and Novel Therapeutics

Massachusetts General Hospital

NCT04130958

RECRUITING NA 30 participants

Treatment of Borderline Personality Disorder With rTMS

University of California, Los Angeles

NCT07197502

RECRUITING Phase 2 10 participants

MDMA in Borderline Personality Disorder

Yale University

NCT06683014

ACTIVE NOT RECRUITING NA 100 participants

Neurofeedback for Borderline Personality Disorder

Kymberly Young

NCT05398627

ACTIVE NOT RECRUITING NA 45 participants

Treatment of Acute Mood Depressive Episode in Borderline Personality Disorder With rTMS

Stanford University

NCT04870255

ACTIVE NOT RECRUITING NA 30 participants

Personality Change Study for Borderline Personality Disorder

Shannon E. Sauer-Zavala

NCT06005129

ACTIVE NOT RECRUITING NA 20 participants

PILOT Phase: BPD Study

University of California, Los Angeles

NCT07223619

COMPLETED Phase 2 201 participants

Evaluating the Safety and Tolerability of Brexpiprazole in the Treatment of Adults With Borderline Personality Disorder (BPD)

Otsuka Pharmaceutical Development & Commercialization

NCT04186403

COMPLETED Phase 2 99 participants

Treatment of Suicidal Women With Borderline Personality Disorder

University of Washington

NCT00183651

COMPLETED NA 93 participants

Preschooler Emotion Regulation in the Context of Maternal Borderline Personality Disorder

University of Oregon

NCT03060902

COMPLETED NA 61 participants

An 18-Month Psychotherapy of Borderline Personality Disorder

Weill Medical College of Cornell University

NCT03329677

COMPLETED 48 participants

fMRI in Impulsivity

Boehringer Ingelheim

NCT02755181

COMPLETED Phase 1 20 participants

Creativity Group for Borderline Personality Disorder

State University of New York - Upstate Medical University

NCT01343550

COMPLETED NA 3 participants

Measuring the Impact of Real Time fMRI Neurofeedback in Borderline Personality Disorder

Yale University

NCT04306341

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 4

Named interventions

Most-linked intervention names on Borderline Personality Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Transcranial Magnetic Stimulation (TMS) Device
2 trials
real time fMRI neurofeedback Behavioral
1 trials
Transference-focused Psychotherapy (TFP) Other
1 trials
Dialectical Behavior Therapy Skills Behavioral
1 trials
Group Skills DBT with no DBT individual sessions (DBT-S) Behavioral
1 trials
Individual DBT with no DBT group sessions (DBT-I) Behavioral
1 trials
Standard dialectical behavior therapy (SDBT) Behavioral
1 trials
creativity group Other
1 trials

US sites by state

Facility locations filed on Borderline Personality Disorder trials. A trial with sites in several states counts in each.

New York 4 trials
Connecticut 3 trials
California 3 trials
Pennsylvania 2 trials
Massachusetts 2 trials
Washington 1 trials
Virginia 1 trials
Kentucky 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Borderline Personality Disorder page

17 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 6 Borderline Personality Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Yale University sponsors the most Borderline Personality Disorder trials on record, review their full trial history before evaluating a specific study. See Yale University's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Borderline Personality Disorder condition card totals 17 registered trials; most-linked intervention Transcranial Magnetic Stimulation (TMS); top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.