Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 6 recruiting now official registry

Borderline Personality Disorder clinical trials

6 of 17 indexed Borderline Personality Disorder trials are currently recruiting.

17 US clinical trials · 6 currently recruiting

Borderline Personality Disorder is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Yale University, running 3 of these trials.

The research picture

Borderline Personality Disorder has 17 registered US clinical trials, 6 of them open to new participants right now, about 35% of the total.

6
recruiting participants now
35%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
3
top sponsor: Yale University
Phase 11Phase 24

Active & Recent Trials

17 total, page 1 of 1

RECRUITING NA 600 participants

Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

Massachusetts General Hospital

NCT04296604

RECRUITING Phase 2 150 participants

Mindfulness-based Neurofeedback to Augment Psychotherapy for Adults With Borderline Personality Disorder

Yale University

NCT06446765

RECRUITING NA 130 participants

Cognitive Reappraisal Training for Borderline Personality (BPD)

Icahn School of Medicine at Mount Sinai

NCT06772831

RECRUITING NA 80 participants

Circuit-Based Approach to Suicide: Biomarkers, Predictors, and Novel Therapeutics

Massachusetts General Hospital

NCT04130958

RECRUITING NA 30 participants

Treatment of Borderline Personality Disorder With rTMS

University of California, Los Angeles

NCT07197502

RECRUITING Phase 2 10 participants

MDMA in Borderline Personality Disorder

Yale University

NCT06683014

ACTIVE NOT RECRUITING NA 100 participants

Neurofeedback for Borderline Personality Disorder

Kymberly Young

NCT05398627

ACTIVE NOT RECRUITING NA 45 participants

Treatment of Acute Mood Depressive Episode in Borderline Personality Disorder With rTMS

Stanford University

NCT04870255

ACTIVE NOT RECRUITING NA 30 participants

Personality Change Study for Borderline Personality Disorder

Shannon E. Sauer-Zavala

NCT06005129

ACTIVE NOT RECRUITING NA 20 participants

PILOT Phase: BPD Study

University of California, Los Angeles

NCT07223619

COMPLETED Phase 2 201 participants

Evaluating the Safety and Tolerability of Brexpiprazole in the Treatment of Adults With Borderline Personality Disorder (BPD)

Otsuka Pharmaceutical Development & Commercialization

NCT04186403

COMPLETED Phase 2 99 participants

Treatment of Suicidal Women With Borderline Personality Disorder

University of Washington

NCT00183651

COMPLETED NA 93 participants

Preschooler Emotion Regulation in the Context of Maternal Borderline Personality Disorder

University of Oregon

NCT03060902

COMPLETED NA 61 participants

An 18-Month Psychotherapy of Borderline Personality Disorder

Weill Medical College of Cornell University

NCT03329677

COMPLETED 48 participants

fMRI in Impulsivity

Boehringer Ingelheim

NCT02755181

COMPLETED Phase 1 20 participants

Creativity Group for Borderline Personality Disorder

State University of New York - Upstate Medical University

NCT01343550

COMPLETED NA 3 participants

Measuring the Impact of Real Time fMRI Neurofeedback in Borderline Personality Disorder

Yale University

NCT04306341

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Borderline Personality Disorder Trial Landscape

17 indexed Borderline Personality Disorder studies · 6 recruiting (35%).

Phase mix: 0 late (III/IV) vs 5 early (I/II).

Top sponsor: Yale University (3 trials), 9 others listed. 17 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Borderline Personality Disorder?

PlainTrial tracks 17 US clinical trials for Borderline Personality Disorder, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Borderline Personality Disorder?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.