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ClinicalTrials.gov 10 recruiting now official registry

Benign Prostatic Hyperplasia clinical trials

10 of 30 indexed Benign Prostatic Hyperplasia trials are currently recruiting.

30 US clinical trials · 10 currently recruiting

Benign Prostatic Hyperplasia is the subject of 30 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Urotronic, running 3 of these trials.

The research picture

Benign Prostatic Hyperplasia has 30 registered US clinical trials, 10 of them open to new participants right now, about 33% of the total.

10
recruiting participants now
33%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
3
top sponsor: Urotronic
Phase 12Phase 24Phase 33Phase 41

Active & Recent Trials

30 total, page 1 of 1

RECRUITING 7,500 participants

BPH Global Registry

Société Internationale d'Urologie

NCT05543200

RECRUITING 1,000 participants

Customized TULSA-PRO Ablation Registry

Profound Medical

NCT05001477

RECRUITING 500 participants

OPtilume™ BPH Catheter SystEm for Treatment of Men eXperiencing Symptomatic BPH

Urotronic

NCT06560476

RECRUITING 300 participants

Enhanced Clinical Decisions for Management of Benign Prostatic Hyperplasia Using Patient-Reported Outcomes

Northwestern University

NCT05898932

RECRUITING NA 215 participants

A Clinical Study to Evaluate the Safety and Efficacy of the FloStent in Men With Benign Prostatic Hyperplasia Symptoms

Rivermark Medical

NCT06849258

RECRUITING NA 150 participants

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Axonics

NCT06511141

RECRUITING NA 120 participants

5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy

Beth Israel Deaconess Medical Center

NCT04288427

RECRUITING NA 101 participants

Ambulatory Long Length URodynamics Evaluation

Bright Uro

NCT07425015

RECRUITING NA 92 participants

Safety and Effectiveness of the Optilume® BPH Catheter System in a Post-Market Study

Urotronic

NCT06312722

RECRUITING NA 68 participants

PRescription Exercise for Older Men With Urinary Disease

University of California, San Francisco

NCT06225479

ACTIVE NOT RECRUITING 3,000 participants

Laser Prostatectomy Database and Registry

Indiana Kidney Stone Institute

NCT00159406

ACTIVE NOT RECRUITING NA 240 participants

Expander-2 Trial: Randomized Study to Evaluate Safety & Efficacy of the Urocross® Expander System & Retrieval Sheath

Prodeon Medical

NCT05400980

ACTIVE NOT RECRUITING NA 162 participants

Optilume™ BPH Catheter System in Men With Symptomatic BPH

Urotronic

NCT04131907

ACTIVE NOT RECRUITING NA 125 participants

PRCT001 Aquablation theraPy Outcomes in pRostate Cancer patienTs

PROCEPT BioRobotics

NCT06051942

ACTIVE NOT RECRUITING NA 120 participants

Comparing UroLift Experience Against Rezūm

NeoTract

NCT04338776

ACTIVE NOT RECRUITING NA 45 participants

Investigation of Prostate Artery Embolization Compared to Holmium Laser Enucleation of Prostate

University of Miami

NCT05155891

ACTIVE NOT RECRUITING Phase 2 17 participants

Phase II Study to Evaluate the Safety and Efficacy of Prostatic Artery Embolization

H. Lee Moffitt Cancer Center and Research Institute

NCT04879940

COMPLETED Phase 3 661 participants

The Evaluation of the Safety of a New Drug for Benign Prostatic Hyperplasia Used for 9 Months

Watson Pharmaceuticals

NCT00224133

COMPLETED Phase 3 325 participants

Study to Treat Patients Who Have Signs and Symptoms of Benign Prostatic Hyperplasia (BPH) With Tadalafil Daily

Eli Lilly and Company

NCT00827242

COMPLETED Phase 3 318 participants

A Study of Tadalafil in Men With Benign Prostatic Hyperplasia Symptoms Who Are Being Treated With Alpha Blockers

Eli Lilly and Company

NCT00848081

COMPLETED NA 206 participants

The Safety and Effectiveness of UroLift: LIFT Pivotal Study

NeoTract

NCT01294150

COMPLETED Phase 2 200 participants

Effects of Tadalafil Once a Day for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic Hyperplasia

Eli Lilly and Company

NCT00386009

COMPLETED Phase 4 150 participants

A Long-Term Study Examining the Treatment of Benign Prostatic Hyperplasia With Photoselective Vaporization

American Medical Systems

NCT00465101

COMPLETED Phase 2 134 participants

Botulinum Toxin Injection for the Management of BPH

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00451191

COMPLETED 99 participants

An Observational Study of Radial Access Embolization Procedures Using HydroPearl Microspheres

Terumo Medical Corporation

NCT04272216

COMPLETED Phase 1 61 participants

A Study Evaluating the Effect of Botulinum Toxin Type A on Semen Quality in Patients With Benign Prostatic Hyperplasia

Allergan

NCT00894517

COMPLETED NA 48 participants

A Self-Administered Maneuver to Relieve Symptoms Suggestive of Benign Prostatic Hyperplasia

Kaiser Permanente

NCT01387893

COMPLETED NA 21 participants

Prostate Artery Embolization (PAE) for Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)

University of Minnesota

NCT02930889

COMPLETED Phase 2 20 participants

A Study to Investigate the Effects on Blood Pressure and Pulse Rate of a Single 100mg Dose of Sildenafil in Patients With Benign Prostatic Hyperplasia Who Are Being Treated With Doxazosin

Pfizer's Upjohn has merged with Mylan to form Viatris

NCT00645034

COMPLETED Phase 1 12 participants

Phase 1 Study of the Litx™ BPH System in Patients With Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)

Light Sciences Oncology

NCT00709488

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 4
Phase 3 3
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Benign Prostatic Hyperplasia Trial Landscape

30 indexed Benign Prostatic Hyperplasia studies · 10 recruiting (33%).

Phase mix: 4 late (III/IV) vs 6 early (I/II).

Top sponsor: Urotronic (3 trials), 9 others listed. 30 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Benign Prostatic Hyperplasia?

PlainTrial tracks 30 US clinical trials for Benign Prostatic Hyperplasia, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Benign Prostatic Hyperplasia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.