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NCT04288427 · ClinicalTrials.gov registry record · NA

5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy

A NA study of Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms, sponsored by Beth Israel Deaconess Medical Center.

Recruiting
Registry status
NA
Development phase
120
Enrollment target
1
Study location

NCT04288427 is a NA study of Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms that is actively recruiting participants, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 120 participants, below the 548-participant average among 29 other Benign Prostatic Hyperplasia trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04288427, a NA study of Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms, is actively recruiting participants, sponsored by Beth Israel Deaconess Medical Center.

RECRUITING
Registry status
NA
Development phase
120 participants
Enrollment target
1
Study location

Study Summary

The study is being conducted to learn why some patients with Benign Prostatic Hyperplasia (BPH) do not respond to a commonly used treatment drug, Finasteride. The hope is to find ways to predict which patients will not respond to Finasteride so that, in the future, these patients can be identified prior to offering this treatment and they can be offered alternative treatment strategies in its place. The aim is to see if noninvasive techniques such as MRI can detect inflammation of the prostate to assist with early detection of those who will and who will not respond to Finasteride.

Interventions

  • DRUG Finasteride

Study Locations (1)

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2020-09-25
Est. Completion 2026-11-30
Phase NA

What the Registry Record Tells You About NCT04288427

The ClinicalTrials.gov registry entry for NCT04288427 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 548-participant average among 29 other Benign Prostatic Hyperplasia trials with a reported enrollment target (78% lower). The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.

The record links to 8 conditions, with Benign Prostatic Hyperplasia appearing as the primary indexed condition, and to 1 intervention - of which Finasteride is the first listed.

NCT04288427 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT04288427 about?

NCT04288427 is a clinical study titled "5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy". The study is being conducted to learn why some patients with Benign Prostatic Hyperplasia (BPH) do not respond to a commonly used treatment drug, Finasteride. The hope is to find ways to predict which patients will not respond to Finasteride so that, in the future, these patients can be identified p...

What is the current status of trial NCT04288427?

This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2020-09-25. Estimated completion is 2026-11-30.

What conditions does trial NCT04288427 study?

This clinical trial studies the following conditions: Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms, Prostate Disease, Prostate Hyperplasia, Urinary Obstruction.

What interventions are being tested in trial NCT04288427?

The interventions under investigation include: Finasteride (DRUG).

Who is sponsoring clinical trial NCT04288427?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04288427 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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