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RECRUITING NA

Aphasia Physical EXercise Study: Randomized Trial

NCT07281313 · View on ClinicalTrials.gov ↗

Study Summary

The goal of this clinical trial is to evaluate the effects of a high-intensity exercise program on recovery in individuals with post-stroke aphasia. The high-intensity exercise program has been specifically designed for individuals with post-stroke aphasia and includes an interval training full-body workout, which can increase cardiovascular fitness, improve muscle strength and motor performance, and maximize cognitive and language gains. The main question this study aims to answer is: • Does participation in a high-intensity exercise program lead to changes in physical health, language, cognitive, motor recovery, psychological and/or psychosocial domains? Participants will be randomly assigned to either a high-intensity exercise program (target intervention) or a low-intensity exercise program (control intervention) delivered over 12-weeks in a group setting. Outcome measures will be collected once immediately after the intervention period and once during the following 12-week maintenance period to capture short- and long-term effects of the exercise program.

Interventions

  • BEHAVIORAL High-intensity physical exercise
  • BEHAVIORAL Low-intensity physical exercise

Study Locations (4)

California

  • University of California, Berkeley — Berkeley
  • California State University, East Bay — Hayward
  • University of San Francisco — San Francisco
  • University of California, San Francisco — San Francisco

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2025-12-01
Est. Completion 2030-03-01
Phase NA

Sponsor

University of California, Berkeley

60 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07281313

The ClinicalTrials.gov registry entry for NCT07281313 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Berkeley, which has 60 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 6 conditions, with Aphasia appearing as the primary indexed condition, and to 2 interventions — of which High-intensity physical exercise is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07281313 reports 4 study locations spanning 1 distinct geographic area — top geographies include California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07281313 about?

NCT07281313 is a clinical study titled "Aphasia Physical EXercise Study: Randomized Trial". The goal of this clinical trial is to evaluate the effects of a high-intensity exercise program on recovery in individuals with post-stroke aphasia. The high-intensity exercise program has been specifically designed for individuals with post-stroke aphasia and includes an interval training full-body...

What is the current status of trial NCT07281313?

This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2025-12-01. Estimated completion is 2030-03-01.

What conditions does trial NCT07281313 study?

This clinical trial studies the following conditions: Aphasia, Aphasia, Acquired, Aphasia Following Cerebral Infarction, Aphasia, Fluent, Aphasia, Non-fluent. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07281313?

The interventions under investigation include: High-intensity physical exercise (BEHAVIORAL), Low-intensity physical exercise (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07281313?

This trial is sponsored by University of California, Berkeley, which has 60 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07281313 being conducted?

This trial has 4 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial