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NCT07281313 · ClinicalTrials.gov registry record · NA

Aphasia Physical EXercise Study: Randomized Trial

A NA study of Aphasia and Aphasia, Acquired, sponsored by University of California, Berkeley.

Recruiting
Registry status
NA
Development phase
120
Enrollment target
4
Study locations

NCT07281313: Recruiting NA study of Aphasia and Aphasia, Acquired, sponsored by University of California, Berkeley.

NCT07281313 is a NA study of Aphasia and Aphasia, Acquired that is actively recruiting participants, run by University of California, Berkeley. The registered enrollment target is 120 participants, above the 81-participant average among 42 other Aphasia trials with a reported enrollment target (48% higher). The trial reports 4 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07281313, a NA study of Aphasia and Aphasia, Acquired, is actively recruiting participants, sponsored by University of California, Berkeley.

RECRUITING
Registry status
NA
Development phase
120 participants
Enrollment target
4
Study locations

Study Summary

The goal of this clinical trial is to evaluate the effects of a high-intensity exercise program on recovery in individuals with post-stroke aphasia. The high-intensity exercise program has been specifically designed for individuals with post-stroke aphasia and includes an interval training full-body workout, which can increase cardiovascular fitness, improve muscle strength and motor performance, and maximize cognitive and language gains. The main question this study aims to answer is: • Does participation in a high-intensity exercise program lead to changes in physical health, language, cognitive, motor recovery, psychological and/or psychosocial domains? Participants will be randomly assigned to either a high-intensity exercise program (target intervention) or a low-intensity exercise program (control intervention) delivered over 12-weeks in a group setting. Outcome measures will be collected once immediately after the intervention period and once during the following 12-week maintenance period to capture short- and long-term effects of the exercise program.

Primary Outcome

The Aphasia Quotient from the Western Aphasia Battery (a standardized language test) measures overall severity of language impairment in aphasia and ranges from 0 to 100, with lower scores indicative of more severe aphasia.

Conditions Studied

Aphasia Aphasia, Acquired Aphasia Following Cerebral Infarction Aphasia Non Fluent Aphasia, Fluent Aphasia Following Nontraumatic Intracerebral Hemorrhage

Interventions

  • BEHAVIORAL High-intensity physical exercise
  • BEHAVIORAL Low-intensity physical exercise

Study Locations (4)

California

  • University of California, Berkeley - Berkeley
  • California State University, East Bay - Hayward
  • University of San Francisco - San Francisco
  • University of California, San Francisco - San Francisco

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2025-12-01
Est. Completion 2030-03-01
Phase NA
University of California, Berkeley

72 total trials

What NCT07281313 shows while recruiting

NCT07281313 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, above the 81-participant average among 42 other Aphasia trials with a reported enrollment target (48% higher).

The record links to 6 conditions, with Aphasia appearing as the primary indexed condition, and to 2 interventions - of which High-intensity physical exercise is the first listed.

NCT07281313 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT07281313 about?

NCT07281313 is a clinical study titled "Aphasia Physical EXercise Study: Randomized Trial". The goal of this clinical trial is to evaluate the effects of a high-intensity exercise program on recovery in individuals with post-stroke aphasia. The high-intensity exercise program has been specifically designed for individuals with post-stroke aphasia and includes an interval training full-body...

What is the current status of trial NCT07281313?

This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2025-12-01. Estimated completion is 2030-03-01.

What conditions does trial NCT07281313 study?

This clinical trial studies the following conditions: Aphasia, Aphasia, Acquired, Aphasia Following Cerebral Infarction, Aphasia Non Fluent, Aphasia, Fluent.

What interventions are being tested in trial NCT07281313?

The interventions under investigation include: High-intensity physical exercise (BEHAVIORAL), Low-intensity physical exercise (BEHAVIORAL).

Who is sponsoring clinical trial NCT07281313?

This trial is sponsored by University of California, Berkeley, which has 72 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07281313 being conducted?

This trial has 4 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Aphasia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07281313's enrollment target sits among peer trials

120 6th of 42 higher than 33 of 42 other Aphasia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Aphasia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT07281313

Source: ClinicalTrials.gov NCT07281313, the US trial registry maintained by the National Library of Medicine. NCT07281313 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.