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NCT07036406 · ClinicalTrials.gov registry record · Phase 2

Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)

A Phase 2 study of Aphasia and Aphasia, Acquired, sponsored by Teachers College, Columbia University.

Recruiting
Registry status
Phase 2
Development phase
40
Enrollment target
1
Study location

NCT07036406 is a Phase 2 study of Aphasia and Aphasia, Acquired that is actively recruiting participants, run by Teachers College, Columbia University. The registered enrollment target is 40 participants, below the 83-participant average among 42 other Aphasia trials with a reported enrollment target (52% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07036406, a Phase 2 study of Aphasia and Aphasia, Acquired, is actively recruiting participants, sponsored by Teachers College, Columbia University.

RECRUITING
Registry status
Phase 2
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to compare the effectiveness of traditional Semantic Feature Analysis (SFA) treatment to a modified SFA protocol that includes Metacognitive Strategy Training (SFA+MST) for adults with acquired aphasia. The main questions it aims to answer are: * What are the comparative outcomes in picture naming accuracy and strategy use during picture naming following 2 months of traditional SFA versus SFA + MST in adults with acquired aphasia? * What are the comparative outcomes in percent of informative content and rate of informative content during spontaneous speech production following 2 months of traditional SFA versus SFA + MST in adults with acquired aphasia? Researchers will compare outcomes between these two treatments to see if SFA+MST yields larger effects in picture naming and spontaneous speech outcomes than traditional SFA. Participants will complete: * 5-7 pre-treatment assessment sessions where they will be asked to name pictures, tell stories/describe pictures, answer questions, and complete questionnaires, * 3 treatment sessions of SFA \*OR\* SFA+MST per week for 8 weeks, for a total of 24 sessions, * 7 weekly probes (i.e., short, intermittent assessments throughout the treatment phase), * 3 post-treatment assessment sessions immediately after treatment ends, where they will complete the same assessment tasks as they did pre-treatment (e.g., naming pictures, telling stories, etc.), * 2 retention assessment sessions, one 30 days and the other 60 days following the final treatment session, where they will be asked to name pictures, tell stories/describe pictures, and describe what they learned during the study.

Interventions

  • BEHAVIORAL Semantic Feature Analysis (traditional)
  • BEHAVIORAL Semantic Feature Analysis + Metacognitive Strategy Training

Study Locations (1)

New York

  • Teachers College, Columbia University - New York

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2025-07-28
Est. Completion 2027-07
Phase Phase 2

What the Registry Record Tells You About NCT07036406

The ClinicalTrials.gov registry entry for NCT07036406 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 83-participant average among 42 other Aphasia trials with a reported enrollment target (52% lower). The listed sponsor is Teachers College, Columbia University, which has 25 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Aphasia appearing as the primary indexed condition, and to 2 interventions - of which Semantic Feature Analysis (traditional) is the first listed.

NCT07036406 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT07036406 about?

NCT07036406 is a clinical study titled "Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)". The goal of this clinical trial is to compare the effectiveness of traditional Semantic Feature Analysis (SFA) treatment to a modified SFA protocol that includes Metacognitive Strategy Training (SFA+MST) for adults with acquired aphasia. The main questions it aims to answer are: * What are the comp...

What is the current status of trial NCT07036406?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2025-07-28. Estimated completion is 2027-07.

What conditions does trial NCT07036406 study?

This clinical trial studies the following conditions: Aphasia, Aphasia, Acquired, Aphasia Following Cerebral Infarction, Aphasia Non Fluent, Aphasia, Rehabilitation.

What interventions are being tested in trial NCT07036406?

The interventions under investigation include: Semantic Feature Analysis (traditional) (BEHAVIORAL), Semantic Feature Analysis + Metacognitive Strategy Training (BEHAVIORAL).

Who is sponsoring clinical trial NCT07036406?

This trial is sponsored by Teachers College, Columbia University, which has 25 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07036406 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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