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ClinicalTrials.gov 35 recruiting now official registry

Anatomic Stage I Breast Cancer AJCC v8 clinical trials

35 of 64 indexed Anatomic Stage I Breast Cancer AJCC v8 trials are currently recruiting.

64 US clinical trials · 35 currently recruiting

Anatomic Stage I Breast Cancer AJCC v8 is the subject of 64 registered US clinical trials on ClinicalTrials.gov, 35 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 19 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 12 of these trials.

The research picture

Anatomic Stage I Breast Cancer AJCC v8 has 64 registered US clinical trials, 35 of them open to new participants right now, about 55% of the total.

35
recruiting participants now
55%
of trials open to enrollment
7
in Phase 3–4 (later-stage)
12
top sponsor: M.D. Anderson Cancer Center
Phase 15Phase 214Phase 36Phase 41

Active & Recent Trials

64 total, page 2 of 2

ACTIVE NOT RECRUITING NA 62 participants

Standard Verbal Counseling With or Without a Pictorial Educational Tool for the Reduction of Psychological Morbidity in Patients With Stage 0-IIIA Breast Cancer Receiving Radiation Therapy, COPE Study

OHSU Knight Cancer Institute

NCT04993313

ACTIVE NOT RECRUITING NA 60 participants

A Conversational Agent (Cecebot) to Improve Insomnia in Stage I-III Breast Cancer Survivors

University of Washington

NCT06392789

ACTIVE NOT RECRUITING NA 50 participants

Hypnosedation in Relaxing Patients Undergoing Breast Cancer Surgery

M.D. Anderson Cancer Center

NCT03012399

ACTIVE NOT RECRUITING NA 49 participants

Mindfulness Intervention for Improving Nutrition in the Digital Kitchen Among Stage I-III Breast Cancer Survivors, MIND Trial

Fred Hutchinson Cancer Center

NCT06643455

ACTIVE NOT RECRUITING NA 30 participants

Exercise During Chemotherapy in Older Women With Stage I-III Breast Cancer

M.D. Anderson Cancer Center

NCT05025059

ACTIVE NOT RECRUITING NA 4 participants

Prospective Pilot Study of Robot-assisted Nipple Sparing Mastectomy (RNSM)

Ohio State University Comprehensive Cancer Center

NCT04537312

COMPLETED NA 452 participants

Tibetan Yoga in Improving Fatigue and Sleep in Participants With Stage I-III Breast Cancer

M.D. Anderson Cancer Center

NCT00507923

COMPLETED Phase 2 130 participants

Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel

Ohio State University Comprehensive Cancer Center

NCT04862585

COMPLETED NA 50 participants

An Episodic Future Thinking Intervention to Promote Weight Loss in Breast Cancer Survivors

Ohio State University Comprehensive Cancer Center

NCT05012176

COMPLETED NA 45 participants

An Escape Room Intervention to Help Improve Breast Cancer Patients' Ability to Navigate Online Access to Nutrition Information

Fred Hutchinson Cancer Center

NCT06193070

COMPLETED NA 27 participants

Weight Bearing Exercise in Preventing Frailty in Stage I-IIIA Breast Cancer Survivors

University of Arizona

NCT03708055

COMPLETED NA 23 participants

Acupuncture in Reducing Chemotherapy-Induced Peripheral Neuropathy in Participants With Stage I-III Breast Cancer

Wake Forest University Health Sciences

NCT03505671

COMPLETED Phase 1 15 participants

Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast Cancer

M.D. Anderson Cancer Center

NCT03774472

COMPLETED Phase 1 11 participants

Nilotinib in Preventing Paclitaxel-Induced Peripheral Neuropathy in Patients With Stage I-III Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT04205903

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Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 14
Phase 3 6
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Anatomic Stage I Breast Cancer AJCC v8 Trial Landscape

64 indexed Anatomic Stage I Breast Cancer AJCC v8 studies · 35 recruiting (55%).

Phase mix: 7 late (III/IV) vs 19 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (12 trials), 9 others listed. 14 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Anatomic Stage I Breast Cancer AJCC v8?

PlainTrial tracks 64 US clinical trials for Anatomic Stage I Breast Cancer AJCC v8, of which 35 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Anatomic Stage I Breast Cancer AJCC v8?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.