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2026 data Public-data reference. official source

Advanced Solid Tumors Cancer

Open-data reference.

10 US clinical trials · 4 currently recruiting

Active & Recent Trials

RECRUITING 2,000 participants

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies

Elephas

NCT07327489

RECRUITING Phase 1 134 participants

A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

Nimbus Wadjet

NCT06898450

RECRUITING Phase 1 80 participants

PQ203 in Advanced Malignant Tumors Including Triple Negative Breast Cancer

ProteinQure

NCT07190469

RECRUITING Phase 1 36 participants

ORB-021 In Patients With Advanced Solid Tumors

Orionis Biosciences

NCT06607939

ACTIVE NOT RECRUITING Phase 1 364 participants

Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors

AbbVie

NCT03821935

ACTIVE NOT RECRUITING Phase 1 237 participants

A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors

AbbVie

NCT02099058

ACTIVE NOT RECRUITING Phase 1 163 participants

A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors

AbbVie

NCT02988960

ACTIVE NOT RECRUITING Phase 1 81 participants

Study of Intravenous (IV) ABBV-637 Alone or in Combination With IV Docetaxel/Osimertinib to Assess Adverse Events and Change in Disease Activity in Adult Participants With Relapsed/Refractory (R/R) Solid Tumors

AbbVie

NCT04721015

COMPLETED Phase 1 62 participants

A Study Evaluating the Safety, Pharmacokinetics, and Anti-tumor Activity of ABBV-321 in Subjects With Advanced Solid Tumors Associated With Overexpression of the Epidermal Growth Factor Receptor (EGFR)

AbbVie

NCT03234712

COMPLETED Phase 1 30 participants

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

AbbVie

NCT04196283

Phase Distribution

PhaseTrial count
Early Phase 1 9

Top Sponsors

AbbVie 6 trials
Nimbus Wadjet 1 trials
ProteinQure 1 trials
Elephas 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Advanced Solid Tumors Cancer Trial Landscape

ClinicalTrials.gov lists 10 US studies indexed under Advanced Solid Tumors Cancer, and 4 of those are currently open to recruitment — roughly 40% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Advanced Solid Tumors Cancer shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Advanced Solid Tumors Cancer is led by AbbVie with 6 indexed trials, alongside 4 other organizations in the top contributor list. The list on this page surfaces up to 10 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Advanced Solid Tumors Cancer?

PlainTrial tracks 10 US clinical trials for Advanced Solid Tumors Cancer, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Advanced Solid Tumors Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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