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ClinicalTrials.gov 4 recruiting now early-phase tilt small index

Advanced Solid Tumors Cancer: early-phase trial registry

4 of 10 indexed Advanced Solid Tumors Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,724 of 28,707 conditions by registered trial count.

10 US clinical trials · 4 currently recruiting · #1,724 of 28,707 conditions by registered trial count

Advanced Solid Tumors Cancer: 10 US clinical trials tracked, 4 recruiting.

Advanced Solid Tumors Cancer is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is AbbVie, running 6 of these trials.

Enrollment posture brief

Registry condition advanced-solid-tumors-cancer

OPEN 4 | RECR 40% | LATE 0 | EARLY 9 | RANK #1724 | SPON 6

Nearest open-share peer: Acute Myeloid Leukemia (AML) (40% recruiting · 30 trials)

Acute Leukemia of Ambiguous 80%Achondroplasia40%Advanced Solid Tumors Ca (th…40%Accelerated Phase Chronic My20%Accidental Fall20%
Open-enrollment share among volume-matched conditions near Advanced Solid Tumors Cancer

Advanced Solid Tumors Cancer lists 4 open slots (40% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Advanced Solid Tumors Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Advanced Solid Tumors Cancer is recruiting below its size-band peers.

    4 of 10 indexed trials (40%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Advanced Solid Tumors Cancer research.

    AbbVie accounts for 6 of 10 trials (60%). 5 distinct sponsors appear on at least one study for this condition label.

  3. Typical Advanced Solid Tumors Cancer enrolment sits around 134 participants.

    Median target enrolment is 134 among the 10 trials that report a genuine target (sentinel values excluded). 5 of those (50%) plan for fewer than 100 participants.

  4. Advanced Solid Tumors Cancer research is mostly interventional.

    9 interventional and 1 observational studies make up this index (90% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 19

Open and recent trials

10 total, page 1 of 1

RECRUITING 2,000 participants

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies

Elephas

NCT07327489

RECRUITING Phase 1 134 participants

A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

Nimbus Wadjet

NCT06898450

RECRUITING Phase 1 80 participants

PQ203 in Advanced Malignant Tumors Including Triple Negative Breast Cancer

ProteinQure

NCT07190469

RECRUITING Phase 1 36 participants

ORB-021 In Patients With Advanced Solid Tumors

Orionis Biosciences

NCT06607939

ACTIVE NOT RECRUITING Phase 1 364 participants

Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors

AbbVie

NCT03821935

ACTIVE NOT RECRUITING Phase 1 237 participants

A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors

AbbVie

NCT02099058

ACTIVE NOT RECRUITING Phase 1 163 participants

A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors

AbbVie

NCT02988960

ACTIVE NOT RECRUITING Phase 1 81 participants

Study of Intravenous (IV) ABBV-637 Alone or in Combination With IV Docetaxel/Osimertinib to Assess Adverse Events and Change in Disease Activity in Adult Participants With Relapsed/Refractory (R/R) Solid Tumors

AbbVie

NCT04721015

COMPLETED Phase 1 62 participants

A Study Evaluating the Safety, Pharmacokinetics, and Anti-tumor Activity of ABBV-321 in Subjects With Advanced Solid Tumors Associated With Overexpression of the Epidermal Growth Factor Receptor (EGFR)

AbbVie

NCT03234712

COMPLETED Phase 1 30 participants

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

AbbVie

NCT04196283

Phase Distribution

PhaseTrial count
Phase 1 9

Top Sponsors

AbbVie 6 trials
Nimbus Wadjet 1 trials
ProteinQure 1 trials
Elephas 1 trials

Named interventions

Most-linked intervention names on Advanced Solid Tumors Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

ABBV-181 Drug
2 trials
Osimertinib Drug
2 trials
ABBV-321 Drug
1 trials
Tilsotolimod Drug
1 trials
ABBV-368 Drug
1 trials
ABBV-927 Drug
1 trials
Telisotuzumab vedotin Drug
1 trials
ORB-021 Drug
1 trials

US sites by state

Facility locations filed on Advanced Solid Tumors Cancer trials. A trial with sites in several states counts in each.

Texas 9 trials
North Carolina 6 trials
New York 5 trials
Missouri 5 trials
Illinois 5 trials
California 5 trials
Tennessee 4 trials
Massachusetts 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Advanced Solid Tumors Cancer page

10 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 4 Advanced Solid Tumors Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • AbbVie sponsors the most Advanced Solid Tumors Cancer trials on record, review their full trial history before evaluating a specific study. See AbbVie's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Advanced Solid Tumors Cancer condition card totals 10 registered trials; most-linked intervention ABBV-181; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.