Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Advanced Malignant Neoplasm: early-phase trial registry
3 of 17 indexed Advanced Malignant Neoplasm trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,004 of 28,707 conditions by registered trial count.
17 US clinical trials · 3 currently recruiting · #1,004 of 28,707 conditions by registered trial count
Advanced Malignant Neoplasm: 17 US clinical trials tracked, 3 recruiting.
Advanced Malignant Neoplasm is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 12 of these trials.
Enrollment posture brief
Registry condition advanced-malignant-neoplasm
OPEN 3 | RECR 18% | LATE 1 | EARLY 9 | RANK #1004 | SPON 12
Volume-matched condition peers
Nearest open-share peer: Cachexia (18% recruiting · 17 trials)
Advanced Malignant Neoplasm lists 3 open slots (18% of 17 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Advanced Malignant Neoplasm on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Advanced Malignant Neoplasm is recruiting below its size-band peers.
3 of 17 indexed trials (17.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Advanced Malignant Neoplasm research.
M.D. Anderson Cancer Center accounts for 12 of 17 trials (70.6%). 6 distinct sponsors appear on at least one study for this condition label.
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Typical Advanced Malignant Neoplasm enrolment sits around 141 participants.
Median target enrolment is 141 among the 17 trials that report a genuine target (sentinel values excluded). 5 of those (29.4%) plan for fewer than 100 participants.
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Advanced Malignant Neoplasm research is mostly interventional.
15 interventional and 2 observational studies make up this index (88.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
17 total, page 1 of 1
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
PMV Pharmaceuticals
NCT04585750
First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia
Kura Oncology
NCT04067336
A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies
AtlasMedx, Incorporated
NCT04503265
Preference of Room Setting and Waiting Time in Patients With Advanced, Locally Advanced, or Metastatic Cancer and Their Caregivers Who Are Seen in the Outpatient Supportive/Palliative Care Center
M.D. Anderson Cancer Center
NCT03671226
A Study of Cancer Related Fatigue in Patients With Metastatic Cancer Receiving Anti-PD1 Immunotherapy
M.D. Anderson Cancer Center
NCT03525873
RCT of QPS vs General Information Sheet
M.D. Anderson Cancer Center
NCT03287492
Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease
M.D. Anderson Cancer Center
NCT01552434
Talazoparib in Treating Patients With Recurrent, Refractory, Advanced, or Metastatic Cancers and Alterations in the BRCA Genes
M.D. Anderson Cancer Center
NCT02286687
Financial Distress in Advanced Cancer Patients
M.D. Anderson Cancer Center
NCT04053517
Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor
Deciphera Pharmaceuticals
NCT03069469
Physical Activity and Dexamethasone in Reducing Cancer-Related Fatigue in Patients With Advanced Cancer
M.D. Anderson Cancer Center
NCT02491632
Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer
M.D. Anderson Cancer Center
NCT03021486
Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer
M.D. Anderson Cancer Center
NCT03203525
Cordotomy in Reducing Pain in Patients With Advanced Cancer
M.D. Anderson Cancer Center
NCT04119037
Caregiver Burden, Quality of Life, and Symptom Distress at Different Palliative Cancer Care Settings
M.D. Anderson Cancer Center
NCT04186884
Videos and Questionnaires in Assessing Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During Clinic Visits
M.D. Anderson Cancer Center
NCT03856060
Enhancing Connections Program in Improving Communication Between Patients With Incurable Cancer and Their Children
University of Washington
NCT02650583
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 3 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Advanced Malignant Neoplasm records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Advanced Malignant Neoplasm trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Advanced Malignant Neoplasm page
17 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Advanced Malignant Neoplasm trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- M.D. Anderson Cancer Center sponsors the most Advanced Malignant Neoplasm trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Advanced Malignant Neoplasm condition card totals 17 registered trials; most-linked intervention Questionnaire Administration; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.