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ClinicalTrials.gov 3 recruiting now official registry

Advanced Malignant Neoplasm clinical trials

Every US clinical trial registered for Advanced Malignant Neoplasm — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

17 US clinical trials · 3 currently recruiting

The research picture

Advanced Malignant Neoplasm has 17 registered US clinical trials, 3 of them open to new participants right now — about 18% of the total.

3
recruiting participants now
18%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
12
top sponsor: M.D. Anderson Cancer Center

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING Phase 1 300 participants

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

PMV Pharmaceuticals

NCT04585750

RECRUITING Phase 1 263 participants

First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

Kura Oncology

NCT04067336

RECRUITING Phase 1 122 participants

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

AtlasMedx, Incorporated

NCT04503265

ACTIVE NOT RECRUITING NA 406 participants

Preference of Room Setting and Waiting Time in Patients With Advanced, Locally Advanced, or Metastatic Cancer and Their Caregivers Who Are Seen in the Outpatient Supportive/Palliative Care Center

M.D. Anderson Cancer Center

NCT03671226

ACTIVE NOT RECRUITING Phase 3 212 participants

A Study of Cancer Related Fatigue in Patients With Metastatic Cancer Receiving Anti-PD1 Immunotherapy

M.D. Anderson Cancer Center

NCT03525873

ACTIVE NOT RECRUITING NA 207 participants

RCT of QPS vs General Information Sheet

M.D. Anderson Cancer Center

NCT03287492

ACTIVE NOT RECRUITING Phase 1 155 participants

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

M.D. Anderson Cancer Center

NCT01552434

ACTIVE NOT RECRUITING Phase 2 150 participants

Talazoparib in Treating Patients With Recurrent, Refractory, Advanced, or Metastatic Cancers and Alterations in the BRCA Genes

M.D. Anderson Cancer Center

NCT02286687

ACTIVE NOT RECRUITING 141 participants

Financial Distress in Advanced Cancer Patients

M.D. Anderson Cancer Center

NCT04053517

ACTIVE NOT RECRUITING Phase 1 120 participants

Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor

Deciphera Pharmaceuticals

NCT03069469

ACTIVE NOT RECRUITING Phase 2 90 participants

Physical Activity and Dexamethasone in Reducing Cancer-Related Fatigue in Patients With Advanced Cancer

M.D. Anderson Cancer Center

NCT02491632

ACTIVE NOT RECRUITING Phase 2 70 participants

Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer

M.D. Anderson Cancer Center

NCT03021486

ACTIVE NOT RECRUITING Phase 1 38 participants

Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer

M.D. Anderson Cancer Center

NCT03203525

ACTIVE NOT RECRUITING NA 27 participants

Cordotomy in Reducing Pain in Patients With Advanced Cancer

M.D. Anderson Cancer Center

NCT04119037

COMPLETED 351 participants

Caregiver Burden, Quality of Life, and Symptom Distress at Different Palliative Cancer Care Settings

M.D. Anderson Cancer Center

NCT04186884

COMPLETED NA 125 participants

Videos and Questionnaires in Assessing Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During Clinic Visits

M.D. Anderson Cancer Center

NCT03856060

COMPLETED NA 41 participants

Enhancing Connections Program in Improving Communication Between Patients With Incurable Cancer and Their Children

University of Washington

NCT02650583

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 3
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Advanced Malignant Neoplasm Trial Landscape

ClinicalTrials.gov lists 17 US studies indexed under Advanced Malignant Neoplasm, and 3 of those are currently open to recruitment — roughly 18% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Advanced Malignant Neoplasm shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Advanced Malignant Neoplasm is led by M.D. Anderson Cancer Center with 12 indexed trials, alongside 5 other organizations in the top contributor list. The list on this page surfaces up to 17 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Advanced Malignant Neoplasm?

PlainTrial tracks 17 US clinical trials for Advanced Malignant Neoplasm, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Advanced Malignant Neoplasm?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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