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NCT04641702 · ClinicalTrials.gov registry record · Phase 4
Comprehensive Esophageal Diagnostics Study
A Phase 4 study of Achalasia, sponsored by Emory University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 80
- Enrollment target
- 2
- Study locations
NCT04641702: Recruiting Phase 4 study of Achalasia, sponsored by Emory University.
NCT04641702 is a Phase 4 study of Achalasia that is actively recruiting participants, run by Emory University. The registered enrollment target is 80 participants, below the 130-participant average among 7 other Achalasia trials with a reported enrollment target (38% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04641702, a Phase 4 study of Achalasia, is actively recruiting participants, sponsored by Emory University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 80 participants
- Enrollment target
- 2
- Study locations
Study Summary
The prospective clinical trial will study muscle fibrosis in relation to lower esophageal sphincter (LES) measurements on Functional Lumen Imaging Probe (FLIP) Topography (the novel technology that utilizes impedance planimetry) after pharmacologic challenge. A better understanding of achalasia will allow intervention at an earlier stage.
Primary Outcome
Degree of lower esophageal sphincter contraction and relaxation will be measured
Conditions Studied
Interventions
- DRUG Atropine challenge
- PROCEDURE Esophageal muscle biopsy
Study Locations (2)
Georgia
- Emory University Hospital - Atlanta
- Emory Saint Joseph's Hospital - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2021-03-17 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 4 |
What NCT04641702 shows while recruiting
NCT04641702 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 130-participant average among 7 other Achalasia trials with a reported enrollment target (38% lower).
The record links to 1 condition, with Achalasia appearing as the primary indexed condition, and to 2 interventions - of which Atropine challenge is the first listed.
NCT04641702 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT04641702 about?
NCT04641702 is a clinical study titled "Comprehensive Esophageal Diagnostics Study". The prospective clinical trial will study muscle fibrosis in relation to lower esophageal sphincter (LES) measurements on Functional Lumen Imaging Probe (FLIP) Topography (the novel technology that utilizes impedance planimetry) after pharmacologic challenge. A better understanding of achalasia will...
What is the current status of trial NCT04641702?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 80 participants. The study started on 2021-03-17. Estimated completion is 2026-12-31.
What conditions does trial NCT04641702 study?
This clinical trial studies the following conditions: Achalasia.
What interventions are being tested in trial NCT04641702?
The interventions under investigation include: Atropine challenge (DRUG), Esophageal muscle biopsy (PROCEDURE).
Who is sponsoring clinical trial NCT04641702?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04641702 being conducted?
This trial has 2 study locations across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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