Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT07382544 · ClinicalTrials.gov registry record · Phase 1

Phase 1b Trial of BMS-986504 in Combination With Olaparib in Patients With MTAP Loss

A Phase 1 study of Solid Tumor and Advanced Cancer, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 1
Development phase
36
Enrollment target
1
Study location

NCT07382544: Recruiting Phase 1 study of Solid Tumor and Advanced Cancer, sponsored by M.D. Anderson Cancer Center.

NCT07382544 is a Phase 1 study of Solid Tumor and Advanced Cancer that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 36 participants, below the 221-participant average among 196 other Solid Tumor trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT07382544, a Phase 1 study of Solid Tumor and Advanced Cancer, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 1
Development phase
36 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical research study is to learn about the safety and effects of BMS-986504 in combination with olaparib in patients with advanced solid tumors with MTAP loss.

Primary Outcome

Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0

Interventions

  • DRUG Olaparib
  • DRUG MRTX1719

Study Locations (1)

Texas

  • The University of Texas M. D. Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2026-02-12
Est. Completion 2032-01-31
Phase Phase 1
M.D. Anderson Cancer Center

2,692 total trials

What NCT07382544 shows while recruiting

NCT07382544 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 221-participant average among 196 other Solid Tumor trials with a reported enrollment target (84% lower).

The record links to 2 conditions, with Solid Tumor appearing as the primary indexed condition, and to 2 interventions - of which Olaparib is the first listed.

NCT07382544 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT07382544 about?

NCT07382544 is a clinical study titled "Phase 1b Trial of BMS-986504 in Combination With Olaparib in Patients With MTAP Loss". The goal of this clinical research study is to learn about the safety and effects of BMS-986504 in combination with olaparib in patients with advanced solid tumors with MTAP loss.

What is the current status of trial NCT07382544?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2026-02-12. Estimated completion is 2032-01-31.

What conditions does trial NCT07382544 study?

This clinical trial studies the following conditions: Solid Tumor, Advanced Cancer.

What interventions are being tested in trial NCT07382544?

The interventions under investigation include: Olaparib (DRUG), MRTX1719 (DRUG).

Who is sponsoring clinical trial NCT07382544?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07382544 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Solid Tumor

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07382544's enrollment target sits among peer trials

36 147th of 196 higher than 49 of 196 other Solid Tumor trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Solid Tumor trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00929006 · 36 participants · Early Phase 1

    Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism

  • NCT01891318 · 36 participants · Phase 1

    Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

  • NCT02291848 · 36 participants · Phase 1

    Tumor-Associated Antigen-Specific Cytotoxic T-Lymphocytes for Multiple Myeloma

  • NCT02366819 · 36 participants · Phase 4

    Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT07382544, the US trial registry maintained by the National Library of Medicine. NCT07382544 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.