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NCT04600089 · ClinicalTrials.gov registry record · Phase 2
Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI
A Phase 2 study of Postoperative Pain and Thoracoabdominal Aortic Aneurysm, sponsored by Sam Tyagi.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT04600089: Recruiting Phase 2 study of Postoperative Pain and Thoracoabdominal Aortic Aneurysm, sponsored by Sam Tyagi.
NCT04600089 is a Phase 2 study of Postoperative Pain and Thoracoabdominal Aortic Aneurysm that is actively recruiting participants, run by Sam Tyagi. The registered enrollment target is 30 participants, below the 232-participant average among 120 other Postoperative Pain trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04600089, a Phase 2 study of Postoperative Pain and Thoracoabdominal Aortic Aneurysm, is actively recruiting participants, sponsored by Sam Tyagi.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of this study is to identify the opioid-sparing effects, and pain-reduction potential of low dose, sub-dissociative ketamine on patients undergoing thoracic endovascular aortic repair (TEVAR) procedures receiving naloxone continuous infusion (NCI).
Primary Outcome
Total morphine milligram equivalents (MME) will be assessed every 6 hours for 48 hours.
Conditions Studied
Interventions
- DRUG Ketamine
- DRUG Saline
Study Locations (1)
Kentucky
- University of Kentucky Medical Center - Lexington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2020-12-08 |
| Est. Completion | 2027-08 |
| Phase | Phase 2 |
What NCT04600089 shows while recruiting
NCT04600089 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 232-participant average among 120 other Postoperative Pain trials with a reported enrollment target (87% lower).
The record links to 3 conditions, with Postoperative Pain appearing as the primary indexed condition, and to 2 interventions - of which Ketamine is the first listed.
NCT04600089 reports a single indexed study location in Kentucky.
Frequently Asked Questions
What is clinical trial NCT04600089 about?
NCT04600089 is a clinical study titled "Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI". The objective of this study is to identify the opioid-sparing effects, and pain-reduction potential of low dose, sub-dissociative ketamine on patients undergoing thoracic endovascular aortic repair (TEVAR) procedures receiving naloxone continuous infusion (NCI).
What is the current status of trial NCT04600089?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2020-12-08. Estimated completion is 2027-08.
What conditions does trial NCT04600089 study?
This clinical trial studies the following conditions: Postoperative Pain, Thoracoabdominal Aortic Aneurysm, Descending Aortic Dissection.
What interventions are being tested in trial NCT04600089?
The interventions under investigation include: Ketamine (DRUG), Saline (DRUG).
Who is sponsoring clinical trial NCT04600089?
This trial is sponsored by Sam Tyagi, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04600089 being conducted?
This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04600089's enrollment target sits among peer trials
30 115th of 120 higher than 5 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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