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NCT07222748 · ClinicalTrials.gov registry record · Phase 3
A Study of TLC590 for Postsurgical Pain Following Bunionectomy
A Phase 3 study of Postoperative Pain, sponsored by TLC Biopharmaceuticals.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 300
- Enrollment target
- 4
- Study locations
NCT07222748 is a Phase 3 study of Postoperative Pain that is actively recruiting participants, run by TLC Biopharmaceuticals. The registered enrollment target is 300 participants, above the 227-participant average among 63 other Postoperative Pain trials with a reported enrollment target (32% higher). The trial reports 4 study locations across 2 states.
The verdict
NCT07222748, a Phase 3 study of Postoperative Pain, is actively recruiting participants, sponsored by TLC Biopharmaceuticals.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 300 participants
- Enrollment target
- 4
- Study locations
Study Summary
This is a Phase 3, randomized, double-blind, comparator- and placebo-controlled study to evaluate analgesic efficacy and safety of TLC590 via local infiltration in adult subjects following bunionectomy.
Conditions Studied
Interventions
- DRUG Saline Placebo
- DRUG TLC590
- DRUG Liposomal Bupivacaine
Study Locations (4)
Texas
- First Surgical Hospital - Bellaire
- Memorial Hermann Village - Houston
- Endeavor Clinical Trials - San Antonio
Florida
- Clinical Pharmacology of Miami - Miami
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2025-11-17 |
| Est. Completion | 2026-05 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07222748
The ClinicalTrials.gov registry entry for NCT07222748 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 227-participant average among 63 other Postoperative Pain trials with a reported enrollment target (32% higher). The listed sponsor is TLC Biopharmaceuticals, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Postoperative Pain appearing as the primary indexed condition, and to 3 interventions - of which Saline Placebo is the first listed.
NCT07222748 reports 4 study locations spanning 2 distinct geographic areas - top geographies include Texas, Florida.
Frequently Asked Questions
What is clinical trial NCT07222748 about?
NCT07222748 is a clinical study titled "A Study of TLC590 for Postsurgical Pain Following Bunionectomy". This is a Phase 3, randomized, double-blind, comparator- and placebo-controlled study to evaluate analgesic efficacy and safety of TLC590 via local infiltration in adult subjects following bunionectomy.
What is the current status of trial NCT07222748?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 300 participants. The study started on 2025-11-17. Estimated completion is 2026-05.
What conditions does trial NCT07222748 study?
This clinical trial studies the following conditions: Postoperative Pain.
What interventions are being tested in trial NCT07222748?
The interventions under investigation include: Saline Placebo (DRUG), TLC590 (DRUG), Liposomal Bupivacaine (DRUG).
Who is sponsoring clinical trial NCT07222748?
This trial is sponsored by TLC Biopharmaceuticals, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07222748 being conducted?
This trial has 4 study locations across Florida, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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