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NCT05761860 · ClinicalTrials.gov registry record · Early Phase 1
The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults
A Early Phase 1 study of Pain, sponsored by University of Florida.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 45
- Enrollment target
- 1
- Study location
NCT05761860 is a Early Phase 1 study of Pain that is actively recruiting participants, run by University of Florida. The registered enrollment target is 45 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05761860, a Early Phase 1 study of Pain, is actively recruiting participants, sponsored by University of Florida.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 45 participants
- Enrollment target
- 1
- Study location
Study Summary
Some research suggests that administration of oxytocin with oxycodone may reduce its abuse liability and improve its ability to reduce pain. In a 6-session laboratory study, we will be evaluating the effects of oxycodone and oxytocin (combined and separately, across sessions) on experimentally-induced pain, subjective effects, and decision-making.
Conditions Studied
Interventions
- DRUG OxyCODONE 5 mg Oral Tablet
- DRUG OxyCODONE 2.5 mg Oral Tablet
- OTHER Placebo oxyCODONE Oral Tablet
- DRUG Oxytocin Nasal Spray (48 IU)
- OTHER Placebo Oxytocin Nasal Spray
Study Locations (1)
Florida
- University of Florida - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2023-09-12 |
| Est. Completion | 2026-12 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05761860
The ClinicalTrials.gov registry entry for NCT05761860 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 304-participant average among 374 other Pain trials with a reported enrollment target (85% lower). The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Pain appearing as the primary indexed condition, and to 5 interventions - of which OxyCODONE 5 mg Oral Tablet is the first listed.
NCT05761860 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.
Frequently Asked Questions
What is clinical trial NCT05761860 about?
NCT05761860 is a clinical study titled "The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults". Some research suggests that administration of oxytocin with oxycodone may reduce its abuse liability and improve its ability to reduce pain. In a 6-session laboratory study, we will be evaluating the effects of oxycodone and oxytocin (combined and separately, across sessions) on experimentally-induc...
What is the current status of trial NCT05761860?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 45 participants. The study started on 2023-09-12. Estimated completion is 2026-12.
What conditions does trial NCT05761860 study?
This clinical trial studies the following conditions: Pain.
What interventions are being tested in trial NCT05761860?
The interventions under investigation include: OxyCODONE 5 mg Oral Tablet (DRUG), OxyCODONE 2.5 mg Oral Tablet (DRUG), Placebo oxyCODONE Oral Tablet (OTHER), Oxytocin Nasal Spray (48 IU) (DRUG), Placebo Oxytocin Nasal Spray (OTHER).
Who is sponsoring clinical trial NCT05761860?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05761860 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.