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NCT07277413 · ClinicalTrials.gov registry record · Phase 1
A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
A Phase 1 study of Bladder Cancer and Gastric Adenocarcinoma, sponsored by IDEAYA Biosciences.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 260
- Enrollment target
- 3
- Study locations
NCT07277413: Recruiting Phase 1 study of Bladder Cancer and Gastric Adenocarcinoma, sponsored by IDEAYA Biosciences.
NCT07277413 is a Phase 1 study of Bladder Cancer and Gastric Adenocarcinoma that is actively recruiting participants, run by IDEAYA Biosciences. The registered enrollment target is 260 participants, below the 12,752-participant average among 175 other Bladder Cancer trials with a reported enrollment target (98% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07277413, a Phase 1 study of Bladder Cancer and Gastric Adenocarcinoma, is actively recruiting participants, sponsored by IDEAYA Biosciences.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 260 participants
- Enrollment target
- 3
- Study locations
Study Summary
This is a multicenter clinical study to evaluate the safety, efficacy, and Pharmacokinetics (PK) of IDE892 as monotherapy and in combination with other agents including IDE397 in participants with methylthioadenosine phosphorylase (MTAP)-deleted advanced solid tumors within indications of interest.
Primary Outcome
Incidence of DLTs of IDE892 will be determined in Parts 1 and 3
Conditions Studied
Interventions
- DRUG IDE397
- DRUG IDE892
Study Locations (3)
Texas
- NEXT Oncology Houston - Houston
- NEXT Oncology Dallas - Irving
Virginia
- NEXT Oncology Virginia - Fairfax
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 260 participants |
| Start Date | 2026-02-28 |
| Est. Completion | 2028-04-30 |
| Phase | Phase 1 |
What NCT07277413 shows while recruiting
NCT07277413 is an interventional study that assigns participants to a tested intervention. The registered 260 participants enrollment target is mid-sized for trials with a published cap, below the 12,752-participant average among 175 other Bladder Cancer trials with a reported enrollment target (98% lower).
The record links to 10 conditions, with Bladder Cancer appearing as the primary indexed condition, and to 2 interventions - of which IDE397 is the first listed.
NCT07277413 reports a single indexed study location in Texas, Virginia.
Frequently Asked Questions
What is clinical trial NCT07277413 about?
NCT07277413 is a clinical study titled "A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors". This is a multicenter clinical study to evaluate the safety, efficacy, and Pharmacokinetics (PK) of IDE892 as monotherapy and in combination with other agents including IDE397 in participants with methylthioadenosine phosphorylase (MTAP)-deleted advanced solid tumors within indications of interest.
What is the current status of trial NCT07277413?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 260 participants. The study started on 2026-02-28. Estimated completion is 2028-04-30.
What conditions does trial NCT07277413 study?
This clinical trial studies the following conditions: Bladder Cancer, Gastric Adenocarcinoma, Mesothelioma, Peritoneal Mesothelioma, Pleural Mesothelioma.
What interventions are being tested in trial NCT07277413?
The interventions under investigation include: IDE397 (DRUG), IDE892 (DRUG).
Who is sponsoring clinical trial NCT07277413?
This trial is sponsored by IDEAYA Biosciences, which has 10 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07277413 being conducted?
This trial has 3 study locations across Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Bladder Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07277413's enrollment target sits among peer trials
260 49th of 175 higher than 127 of 175 other Bladder Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Bladder Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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