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NCT07168915 · ClinicalTrials.gov registry record · Phase 1
A Study of V118E in Healthy Participants (V118E-003)
A Phase 1 study of Healthy, sponsored by Merck Sharp & Dohme.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 126
- Enrollment target
- 4
- Study locations
NCT07168915 is a Phase 1 study of Healthy that is actively recruiting participants, run by Merck Sharp & Dohme. The registered enrollment target is 126 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (81% lower). The trial reports 4 study locations across 3 states.
The verdict
NCT07168915, a Phase 1 study of Healthy, is actively recruiting participants, sponsored by Merck Sharp & Dohme.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 126 participants
- Enrollment target
- 4
- Study locations
Study Summary
Researchers are looking for new vaccines to prevent illnesses caused by a type of bacteria called Streptococcus pneumoniae. There are many different types of Streptococcus pneumoniae bacteria, called serotypes. Vaccines contain small parts of certain serotypes. These parts will not cause an infection but help the body create antibodies (proteins) to fight the bacteria. PREVNAR 20™ is a vaccine given to help to prevent disease from Streptococcus pneumoniae bacteria. Researchers designed a new vaccine, V118E, to help prevent disease from Streptococcus pneumoniae bacteria. The goal of this study is to learn how safe V118 formulation E is in Healthy Adults and how well people tolerate it.
Conditions Studied
Interventions
- BIOLOGICAL Saline
- BIOLOGICAL V118E
- BIOLOGICAL PREVNAR 20™
Study Locations (4)
Florida
- Velocity Clinical Research, Hallandale Beach ( Site 0003) - Hallandale
- QPS-MRA, LLC-Early Phase ( Site 0002) - South Miami
Missouri
- Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0004) - Springfield
Texas
- University of Texas Medical Branch ( Site 0001) - Galveston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 126 participants |
| Start Date | 2025-10-08 |
| Est. Completion | 2027-11-12 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07168915
The ClinicalTrials.gov registry entry for NCT07168915 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 126 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (81% lower). The listed sponsor is Merck Sharp & Dohme, which has 558 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 3 interventions - of which Saline is the first listed.
NCT07168915 reports 4 study locations spanning 3 distinct geographic areas - top geographies include Florida, Missouri, Texas.
Frequently Asked Questions
What is clinical trial NCT07168915 about?
NCT07168915 is a clinical study titled "A Study of V118E in Healthy Participants (V118E-003)". Researchers are looking for new vaccines to prevent illnesses caused by a type of bacteria called Streptococcus pneumoniae. There are many different types of Streptococcus pneumoniae bacteria, called serotypes. Vaccines contain small parts of certain serotypes. These parts will not cause an infectio...
What is the current status of trial NCT07168915?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 126 participants. The study started on 2025-10-08. Estimated completion is 2027-11-12.
What conditions does trial NCT07168915 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT07168915?
The interventions under investigation include: Saline (BIOLOGICAL), V118E (BIOLOGICAL), PREVNAR 20™ (BIOLOGICAL).
Who is sponsoring clinical trial NCT07168915?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07168915 being conducted?
This trial has 4 study locations across Florida, Missouri, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.