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NCT04690348 · ClinicalTrials.gov registry record · Phase 2

Intracavitary Carrier-embedded Cs131 Brachytherapy for Recurrent Brain Metastases: a Randomized Phase II Study

A Phase 2 study of Recurrent Brain Metastases, sponsored by Memorial Sloan Kettering Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
103
Enrollment target
6
Study locations

NCT04690348 is a Phase 2 study of Recurrent Brain Metastases that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 103 participants. The trial reports 6 study locations across 3 states.

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The verdict

NCT04690348, a Phase 2 study of Recurrent Brain Metastases, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
103 participants
Enrollment target
6
Study locations

Study Summary

The purpose of this study is to see if Cs-131 brachytherapy is effective in people with recurrent brain cancer who are scheduled to have brain surgery for removal of their tumor(s). The researchers would like to see whether Cs-131 prevents brain tumors from growing back after surgery.The researchers will compare Cs-131 brachytherapy (which occurs during brain surgery) with the usual approach of brain surgery without brachytherapy. The researchers will compare both the effectiveness and safety of the two approaches.

Conditions Studied

Interventions

  • PROCEDURE Craniotomy
  • RADIATION Cesium-131 brachytherapy

Study Locations (6)

New York

  • Memorial Sloan Kettering Commack (Consent Only) - Commack
  • Memorial Sloan Kettering Cancer Center - New York
  • Memorial Sloan Kettering Nassau (Limited Protocol Activities) - Uniondale

New Jersey

  • Memorial Sloan Kettering at Basking Ridge (Consent Only) - Basking Ridge
  • Memorial Sloan Kettering Monmouth (Consent Only) - Middletown

Florida

  • Baptist Health South Florida - Miami

Trial Details

FieldValue
Enrollment Target 103 participants
Start Date 2020-12-24
Est. Completion 2026-12
Phase Phase 2

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT04690348

The ClinicalTrials.gov registry entry for NCT04690348 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 103 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Recurrent Brain Metastases appearing as the primary indexed condition, and to 2 interventions - of which Craniotomy is the first listed.

NCT04690348 reports 6 study locations spanning 3 distinct geographic areas - top geographies include New York, New Jersey, Florida.

Frequently Asked Questions

What is clinical trial NCT04690348 about?

NCT04690348 is a clinical study titled "Intracavitary Carrier-embedded Cs131 Brachytherapy for Recurrent Brain Metastases: a Randomized Phase II Study". The purpose of this study is to see if Cs-131 brachytherapy is effective in people with recurrent brain cancer who are scheduled to have brain surgery for removal of their tumor(s). The researchers would like to see whether Cs-131 prevents brain tumors from growing back after surgery.The researchers...

What is the current status of trial NCT04690348?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 103 participants. The study started on 2020-12-24. Estimated completion is 2026-12.

What conditions does trial NCT04690348 study?

This clinical trial studies the following conditions: Recurrent Brain Metastases.

What interventions are being tested in trial NCT04690348?

The interventions under investigation include: Craniotomy (PROCEDURE), Cesium-131 brachytherapy (RADIATION).

Who is sponsoring clinical trial NCT04690348?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04690348 being conducted?

This trial has 6 study locations across Florida, New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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