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NCT06979362 · ClinicalTrials.gov registry record · Phase 2

A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

A Phase 2 study of Heart Failure, sponsored by Novo Nordisk A/S.

Recruiting
Registry status
Phase 2
Development phase
200
Enrollment target
20
Study locations

NCT06979362: Recruiting Phase 2 study of Heart Failure, sponsored by Novo Nordisk A/S.

NCT06979362 is a Phase 2 study of Heart Failure that is actively recruiting participants, run by Novo Nordisk A/S. The registered enrollment target is 200 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (90% lower). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06979362, a Phase 2 study of Heart Failure, is actively recruiting participants, sponsored by Novo Nordisk A/S.

RECRUITING
Registry status
Phase 2
Development phase
200 participants
Enrollment target
20
Study locations

Study Summary

This study will look into how CDR132L (a potential new medicine) works on the structure and function of the heart in people living with heart failure. Participants will either get CDR132L or placebo (a medicine which has no effect on the body), which treatment the participants get is decided by chance. The study will last for about 60 weeks.

Primary Outcome

Measured as ratio to baseline.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG CDR132L

Study Locations (20)

California

  • Valley Clinical Trials - Covina
  • UCSD NAFLD Research Center - La Jolla
  • Valley Clinical Trials - Northridge
  • University of California, San Francisco - San Francisco
  • University of California San Francisco UCSF - San Francisco
  • Harbor-UCLA Medical Center - Torrance

Florida

  • Inpatient Research Clinic LLC - Miami Lakes
  • AdventHealth Orlando - Orlando
  • Guardian Research Org LLC - Winter Park

Arizona

  • TMC Hlthcr Clin Res Office - Tucson
  • Pima Heart and Vascular - Tucson

Alabama

  • Univ of Alabama Birmingham - Birmingham

Colorado

  • CPC Clinical Research & Community Health - Aurora

Kentucky

  • UofL Health Care Outpatient - Louisville

Michigan

  • Henry Ford Hospital_Detroit - Detroit

Minnesota

  • University of Minnesota_Minneapolis_1 - Minneapolis

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2025-06-27
Est. Completion 2028-01-23
Phase Phase 2
Novo Nordisk A/S

431 total trials

What NCT06979362 shows while recruiting

NCT06979362 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (90% lower).

The record links to 1 condition, with Heart Failure appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06979362 names 20 study sites across 12 states, led by California, Florida, Arizona.

Frequently Asked Questions

What is clinical trial NCT06979362 about?

NCT06979362 is a clinical study titled "A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy". This study will look into how CDR132L (a potential new medicine) works on the structure and function of the heart in people living with heart failure. Participants will either get CDR132L or placebo (a medicine which has no effect on the body), which treatment the participants get is decided by chan...

What is the current status of trial NCT06979362?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2025-06-27. Estimated completion is 2028-01-23.

What conditions does trial NCT06979362 study?

This clinical trial studies the following conditions: Heart Failure.

What interventions are being tested in trial NCT06979362?

The interventions under investigation include: Placebo (DRUG), CDR132L (DRUG).

Who is sponsoring clinical trial NCT06979362?

This trial is sponsored by Novo Nordisk A/S, which has 431 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06979362 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Heart Failure

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06979362's enrollment target sits among peer trials

200 165th of 397 higher than 229 of 397 other Heart Failure trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06979362, the US trial registry maintained by the National Library of Medicine. NCT06979362 (mid enrollment · wide site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.