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NCT02995252 · ClinicalTrials.gov registry record
The HOPE Study: Characterizing Patients With Hepatitis B and C
A clinical trial of Hepatitis C and Hepatitis B， Chronic, sponsored by University of Maryland, Baltimore.
- Recruiting
- Registry status
- 550
- Enrollment target
- 2
- Study locations
NCT02995252: Recruiting study of Hepatitis C and Hepatitis B， Chronic, sponsored by University of Maryland, Baltimore.
NCT02995252 is a study of Hepatitis C and Hepatitis B， Chronic that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 550 participants, below the 1,885-participant average among 106 other Hepatitis C trials with a reported enrollment target (71% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02995252, a study of Hepatitis C and Hepatitis B， Chronic, is actively recruiting participants, sponsored by University of Maryland, Baltimore.
- RECRUITING
- Registry status
- 550 participants
- Enrollment target
- 2
- Study locations
Study Summary
This is an observational, longitudinal, prospective study for sample collection and evaluation for future therapy or disease progression of chronic hepatitis B and C. Participants will be seen on an annual basis with optional additional visits for up to 10 years and provide samples for research and evaluation of disease progression. In addition, there is a longitudinal sub-study for treatment of hepatitis B that will involve 2 years of treatment with tenofovir alafenamide and blood collections with optional liver biopsies.
Primary Outcome
Participants will be provided with the nucleotide analogue, tenofovir alafenamide. Change in liver stiffness as measured by transient elastography (FibroScan) before starting tenofovir alafenamide, at time of liver enzyme normalization, and at 2 years of treatment.
Conditions Studied
Interventions
- PROCEDURE Liver Biopsy
- OTHER Blood draws
- DRUG Tenofovir Alafenamide
- OTHER Knowledge Index Questionnaire
- OTHER Liver transient elastography (FibroScan)
Study Locations (2)
Maryland
- Institute of Human Virology, University of Maryland School of Medicine - Baltimore
Virginia
- Dr Huong Dang, Medical Practice - Falls Church
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 550 participants |
| Start Date | 2014-12 |
| Est. Completion | 2034-12 |
What NCT02995252 shows while recruiting
NCT02995252 is an observational study that tracks outcomes without assigning an intervention. The registered 550 participants enrollment target is mid-sized for trials with a published cap, below the 1,885-participant average among 106 other Hepatitis C trials with a reported enrollment target (71% lower).
The record links to 2 conditions, with Hepatitis C appearing as the primary indexed condition, and to 5 interventions - of which Liver Biopsy is the first listed.
NCT02995252 reports a single indexed study location in Maryland, Virginia.
Frequently Asked Questions
What is clinical trial NCT02995252 about?
NCT02995252 is a clinical study titled "The HOPE Study: Characterizing Patients With Hepatitis B and C". This is an observational, longitudinal, prospective study for sample collection and evaluation for future therapy or disease progression of chronic hepatitis B and C. Participants will be seen on an annual basis with optional additional visits for up to 10 years and provide samples for research and ...
What is the current status of trial NCT02995252?
This trial is currently recruiting. The enrollment target is 550 participants. The study started on 2014-12. Estimated completion is 2034-12.
What conditions does trial NCT02995252 study?
This clinical trial studies the following conditions: Hepatitis C, Hepatitis B， Chronic.
What interventions are being tested in trial NCT02995252?
The interventions under investigation include: Liver Biopsy (PROCEDURE), Blood draws (OTHER), Tenofovir Alafenamide (DRUG), Knowledge Index Questionnaire (OTHER), Liver transient elastography (FibroScan) (OTHER).
Who is sponsoring clinical trial NCT02995252?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02995252 being conducted?
This trial has 2 study locations across Maryland, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hepatitis C
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02995252's enrollment target sits among peer trials
550 18th of 106 higher than 89 of 106 other Hepatitis C trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hepatitis C trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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