Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 1

SNV4818 in Participants With Advanced Solid Tumors

NCT06736704 · View on ClinicalTrials.gov ↗

Study Summary

This study is testing a new medicine, SNV4818, for people with advanced cancers. The researchers want to find out if SNV4818 is safe, well-tolerated, and effective in treating solid tumors. They are investigating different doses in order to find the safest and most effective one.

Conditions Studied

Interventions

  • DRUG SNV4818
  • DRUG Fulvestrant
  • DRUG Palbociclib

Study Locations (12)

New South Wales

  • Chris O'Brien Lifehouse — Camperdown
  • Scientia Clinical Research — Randwick

Victoria

  • Monash Health — Clayton
  • Peter MacCallum Cancer Centre — Melbourne

Ontario

  • The Ottawa Hospital Cancer Centre — Ottawa
  • University Health Network, Princess Margaret Cancer Centre — Toronto

California

  • The Angeles Clinic and Research Institute, A Cedars-Sinai Affiliate — Los Angeles

Massachusetts

  • Massachusetts General Hospital — Boston

Pennsylvania

  • Thomas Jefferson University-Sidney Kimmel Cancer Center — Philadelphia

Tennessee

  • Sarah Cannon Research Institute — Nashville

Texas

  • The University of Texas M.D. Anderson Cancer Center — Houston

Trial Details

FieldValue
Enrollment Target 320 participants
Start Date 2025-02-20
Est. Completion 2027-06
Phase Phase 1

Sponsor

Pikavation Therapeutics

29 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06736704

The ClinicalTrials.gov registry entry for NCT06736704 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 320 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pikavation Therapeutics, which has 29 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Advanced Solid Tumors appearing as the primary indexed condition, and to 3 interventions — of which SNV4818 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06736704 reports 12 study locations spanning 9 distinct geographic areas — top geographies include New South Wales, Victoria, Ontario. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06736704 about?

NCT06736704 is a clinical study titled "SNV4818 in Participants With Advanced Solid Tumors". This study is testing a new medicine, SNV4818, for people with advanced cancers. The researchers want to find out if SNV4818 is safe, well-tolerated, and effective in treating solid tumors. They are investigating different doses in order to find the safest and most effective one.

What is the current status of trial NCT06736704?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 320 participants. The study started on 2025-02-20. Estimated completion is 2027-06.

What conditions does trial NCT06736704 study?

This clinical trial studies the following conditions: Advanced Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06736704?

The interventions under investigation include: SNV4818 (DRUG), Fulvestrant (DRUG), Palbociclib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06736704?

This trial is sponsored by Pikavation Therapeutics, which has 29 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06736704 being conducted?

This trial has 12 study locations across California, Massachusetts, Pennsylvania, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial