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JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration
NCT06973564 · View on ClinicalTrials.gov ↗
Study Summary
This study is to evaluate the safety and tolerability of pan-KRAS inhibitor JAB-23E73 in adult participants with advanced solid tumors
Conditions Studied
Interventions
- DRUG JAB-23E73
Study Locations (4)
Minnesota
- Mayo Clinic — Rochester
Missouri
- Washington University — St Louis
Ohio
- Cleveland Clinic Foundation — Cleveland
Utah
- Huntsman Cancer Institute — Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 294 participants |
| Start Date | 2025-05-29 |
| Est. Completion | 2028-02 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06973564
The ClinicalTrials.gov registry entry for NCT06973564 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 294 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jacobio Pharmaceuticals Co., which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Advanced Solid Tumors appearing as the primary indexed condition, and to 1 intervention — of which JAB-23E73 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06973564 reports 4 study locations spanning 4 distinct geographic areas — top geographies include Minnesota, Missouri, Ohio. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06973564 about?
NCT06973564 is a clinical study titled "JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration". This study is to evaluate the safety and tolerability of pan-KRAS inhibitor JAB-23E73 in adult participants with advanced solid tumors
What is the current status of trial NCT06973564?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 294 participants. The study started on 2025-05-29. Estimated completion is 2028-02.
What conditions does trial NCT06973564 study?
This clinical trial studies the following conditions: Advanced Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06973564?
The interventions under investigation include: JAB-23E73 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06973564?
This trial is sponsored by Jacobio Pharmaceuticals Co., which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06973564 being conducted?
This trial has 4 study locations across Minnesota, Missouri, Ohio, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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