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NCT06866691 · ClinicalTrials.gov registry record · Phase 4

Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide

A Phase 4 study of Traumatic Brain Injury, sponsored by Wake Forest University Health Sciences.

Recruiting
Registry status
Phase 4
Development phase
600
Enrollment target
1
Study location

NCT06866691 is a Phase 4 study of Traumatic Brain Injury that is actively recruiting participants, run by Wake Forest University Health Sciences. The registered enrollment target is 600 participants, above the 274-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target (119% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT06866691, a Phase 4 study of Traumatic Brain Injury, is actively recruiting participants, sponsored by Wake Forest University Health Sciences.

RECRUITING
Registry status
Phase 4
Development phase
600 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to assess the incidence of early post-traumatic seizures. The study will also assess the benefit of lacosamide compared to levetiracetam in regards to agitation and behavioral adverse effects in patients with moderate to severe traumatic brain injury requiring seizure prophylaxis.

Conditions Studied

Traumatic Brain Injury

Interventions

  • DRUG levetiracetam
  • DRUG lacosamide

Study Locations (1)

North Carolina

  • Wake Forest University Health Sciences - Winston-Salem

Trial Details

FieldValue
Enrollment Target 600 participants
Start Date 2025-04-18
Est. Completion 2027-04
Phase Phase 4

Sponsor

Wake Forest University Health Sciences

1,140 total trials

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What the Registry Record Tells You About NCT06866691

The ClinicalTrials.gov registry entry for NCT06866691 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 600 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 274-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target (119% higher). The listed sponsor is Wake Forest University Health Sciences, which has 1,140 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Traumatic Brain Injury appearing as the primary indexed condition, and to 2 interventions - of which levetiracetam is the first listed.

NCT06866691 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT06866691 about?

NCT06866691 is a clinical study titled "Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide". The purpose of this study is to assess the incidence of early post-traumatic seizures. The study will also assess the benefit of lacosamide compared to levetiracetam in regards to agitation and behavioral adverse effects in patients with moderate to severe traumatic brain injury requiring seizure pr...

What is the current status of trial NCT06866691?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 600 participants. The study started on 2025-04-18. Estimated completion is 2027-04.

What conditions does trial NCT06866691 study?

This clinical trial studies the following conditions: Traumatic Brain Injury.

What interventions are being tested in trial NCT06866691?

The interventions under investigation include: levetiracetam (DRUG), lacosamide (DRUG).

Who is sponsoring clinical trial NCT06866691?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06866691 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.