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NCT06667414 · ClinicalTrials.gov registry record

Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers

A clinical trial of Huntington Disease, sponsored by Hoffmann-La Roche.

Recruiting
Registry status
600
Enrollment target
20
Study locations

NCT06667414: Recruiting study of Huntington Disease, sponsored by Hoffmann-La Roche.

NCT06667414 is a study of Huntington Disease that is actively recruiting participants, run by Hoffmann-La Roche. The registered enrollment target is 600 participants, roughly in line with the 618-participant average among 35 other Huntington Disease trials with a reported enrollment target. The trial reports 20 study locations across 18 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06667414, a study of Huntington Disease, is actively recruiting participants, sponsored by Hoffmann-La Roche.

RECRUITING
Registry status
600 participants
Enrollment target
20
Study locations

Study Summary

For participation in this epidemiological study, a single-day visit at the study site is required. Participants will be recruited from Huntington Disease clinics, and they will be asked to answer questions regarding their demographics, including sex, age, race and ethnicity, and their medical and medication history. At the end of the visit, a blood sample will be drawn to allow testing with a sequencing assay that is specifically designed for phasing single nucleotide polymorphisms (SNPs) on the wild-type Huntington (wtHTT) and mutant Huntington (mHTT) alleles.

Conditions Studied

Study Locations (20)

California

  • University of California San Diego - La Jolla
  • University of California Davis Medical System - Sacramento

New South Wales

  • Calvary Health Care Bethlehem - Caulfield South
  • Westmead Hospital - Westmead

Alabama

  • Uab Medicine - Birmingham

Arizona

  • Barrow Neurological Institute - Phoenix

Colorado

  • CenExel Rocky Mountain Clinical Research, LLC - Englewood

Florida

  • University of South Florida - Tampa

Illinois

  • Northwestern University - Chicago

Iowa

  • University of Iowa Hospitals and Clinics - Iowa City

Trial Details

FieldValue
Enrollment Target 600 participants
Start Date 2024-09-02
Est. Completion 2028-09-24
Hoffmann-La Roche

909 total trials

What NCT06667414 shows while recruiting

NCT06667414 is an observational study that tracks outcomes without assigning an intervention. The registered 600 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 618-participant average among 35 other Huntington Disease trials with a reported enrollment target.

The record links to 1 condition, with Huntington Disease appearing as the primary indexed condition, and to 0 interventions.

NCT06667414 names 20 study sites across 18 states, led by California, New South Wales, Alabama.

Frequently Asked Questions

What is clinical trial NCT06667414 about?

NCT06667414 is a clinical study titled "Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers". For participation in this epidemiological study, a single-day visit at the study site is required. Participants will be recruited from Huntington Disease clinics, and they will be asked to answer questions regarding their demographics, including sex, age, race and ethnicity, and their medical and me...

What is the current status of trial NCT06667414?

This trial is currently recruiting. The enrollment target is 600 participants. The study started on 2024-09-02. Estimated completion is 2028-09-24.

What conditions does trial NCT06667414 study?

This clinical trial studies the following conditions: Huntington Disease.

Who is sponsoring clinical trial NCT06667414?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06667414 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Huntington Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06667414's enrollment target sits among peer trials

600 8th of 35 higher than 27 of 35 other Huntington Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Huntington Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06667414, the US trial registry maintained by the National Library of Medicine. NCT06667414 (mid enrollment · wide site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.