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NCT06082713 · ClinicalTrials.gov registry record
Extracellular Vesicles for HD
A clinical trial of Huntington Disease, sponsored by University of Central Florida.
- Recruiting
- Registry status
- 100
- Enrollment target
- 1
- Study location
NCT06082713 is a study of Huntington Disease that is actively recruiting participants, run by University of Central Florida. The registered enrollment target is 100 participants, below the 633-participant average among 35 other Huntington Disease trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06082713, a study of Huntington Disease, is actively recruiting participants, sponsored by University of Central Florida.
- RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary objective of this study is to discover blood-based biomarker of brain Huntingtin (HTT) protein using extracellular vesicles to be used in evaluating target engagement in HTT lowering clinical trials. Secondary objectives of this study include developing more accurate biomarkers of Huntington disease (HD) progression or conversion and to develop standard practices for extracellular vesicle biomarker discovery research. The investigators hypothesize that brain-derived extracellular vesicles (EVs) isolated from human biofluids contain biological cargo specific to their tissue of origin that could allow their use as brain biomarkers for HD. EVs are lipid bilayer-delimited particles that are naturally released from cells in the brain. The investigators will investigate if EVs contents reflect the pathological alterations occurring with disease progression when compared with EVs isolated from biofluids of healthy non-HD persons.
Conditions Studied
Study Locations (1)
Florida
- University of Central Florida - Orlando
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2023-10-25 |
| Est. Completion | 2031-11 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06082713
The ClinicalTrials.gov registry entry for NCT06082713 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 633-participant average among 35 other Huntington Disease trials with a reported enrollment target (84% lower). The listed sponsor is University of Central Florida, which has 91 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Huntington Disease appearing as the primary indexed condition, and to 0 interventions.
NCT06082713 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.
Frequently Asked Questions
What is clinical trial NCT06082713 about?
NCT06082713 is a clinical study titled "Extracellular Vesicles for HD". The primary objective of this study is to discover blood-based biomarker of brain Huntingtin (HTT) protein using extracellular vesicles to be used in evaluating target engagement in HTT lowering clinical trials. Secondary objectives of this study include developing more accurate biomarkers of Hunti...
What is the current status of trial NCT06082713?
This trial is currently recruiting. The enrollment target is 100 participants. The study started on 2023-10-25. Estimated completion is 2031-11.
What conditions does trial NCT06082713 study?
This clinical trial studies the following conditions: Huntington Disease.
Who is sponsoring clinical trial NCT06082713?
This trial is sponsored by University of Central Florida, which has 91 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06082713 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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