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NCT06610877 · ClinicalTrials.gov registry record · NA
Ultrasound Neuromodulation in Essential Tremor
A NA study of Essential Tremor and Neuromodulation, sponsored by University of California, San Francisco.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06610877: Recruiting NA study of Essential Tremor and Neuromodulation, sponsored by University of California, San Francisco.
NCT06610877 is a NA study of Essential Tremor and Neuromodulation that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 60 participants, below the 401-participant average among 41 other Essential Tremor trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06610877, a NA study of Essential Tremor and Neuromodulation, is actively recruiting participants, sponsored by University of California, San Francisco.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is being done to test whether low-intensity focused ultrasound (LIFU) (low energy sound waves) cause temporary changes in brain activity and behavior when directed at particular parts of the brain. By targeting LIFU to the parts of the brain thought to be responsible for essential tremor (ET), and measuring any associated improvement in tremor, the investigators hope to show that LIFU can be a useful tool for studying the brain circuits responsible for tremor and other brain disorders.
Primary Outcome
The investigators will screen ultrasound parameters through repeated sonications within the same session (up to 25, depending on patient response) to determine which parameter set is most effective at reducing tremor in each participant as measured by wrist accelerometers (reduction in tremor power from baseline in the characteristic ET range of 4-12 Hz). Stimulation protocols will consist of 5 seconds of active stimulation followed by 10 seconds of no stimulation repeated four times (total 60 s
Conditions Studied
Interventions
- DEVICE Focused Ultrasound Neuromodulation - Sham Control
- DEVICE Focused ultrasound neuromodulation
Study Locations (1)
California
- Pritzker Building, UCSF - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2024-10-01 |
| Est. Completion | 2027-03 |
| Phase | NA |
What NCT06610877 shows while recruiting
NCT06610877 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 401-participant average among 41 other Essential Tremor trials with a reported enrollment target (85% lower).
The record links to 2 conditions, with Essential Tremor appearing as the primary indexed condition, and to 2 interventions - of which Focused Ultrasound Neuromodulation - Sham Control is the first listed.
NCT06610877 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06610877 about?
NCT06610877 is a clinical study titled "Ultrasound Neuromodulation in Essential Tremor". This study is being done to test whether low-intensity focused ultrasound (LIFU) (low energy sound waves) cause temporary changes in brain activity and behavior when directed at particular parts of the brain. By targeting LIFU to the parts of the brain thought to be responsible for essential tremor ...
What is the current status of trial NCT06610877?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2024-10-01. Estimated completion is 2027-03.
What conditions does trial NCT06610877 study?
This clinical trial studies the following conditions: Essential Tremor, Neuromodulation.
What interventions are being tested in trial NCT06610877?
The interventions under investigation include: Focused Ultrasound Neuromodulation - Sham Control (DEVICE), Focused ultrasound neuromodulation (DEVICE).
Who is sponsoring clinical trial NCT06610877?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06610877 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Essential Tremor
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06610877's enrollment target sits among peer trials
60 22nd of 41 higher than 19 of 41 other Essential Tremor trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Essential Tremor trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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