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NCT06580587 · ClinicalTrials.gov registry record · Phase 1

A Study of MK-8527 in Healthy Lactating Female Participants (MK-8527-009)

A Phase 1 study of Healthy and HIV Pre-exposure Prophylaxis, sponsored by Merck Sharp & Dohme.

Active
Registry status
Phase 1
Development phase
12
Enrollment target
2
Study locations

NCT06580587 is a Phase 1 study of Healthy and HIV Pre-exposure Prophylaxis that is active but no longer recruiting, run by Merck Sharp & Dohme. The registered enrollment target is 12 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT06580587, a Phase 1 study of Healthy and HIV Pre-exposure Prophylaxis, is active but no longer recruiting, sponsored by Merck Sharp & Dohme.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
12 participants
Enrollment target
2
Study locations

Study Summary

The goal of this study is to learn how MK-8527 moves through the healthy person's body over time. Researchers will measure for the amount of MK-8527 in breast milk that the baby will receive at many time points.

Conditions Studied

Healthy HIV Pre-exposure Prophylaxis

Interventions

  • DRUG MK-8527

Study Locations (2)

Missouri

  • Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0002) - Springfield

Pennsylvania

  • University of Pittsburgh Medical Center Magee-Womens Hospital ( Site 0001) - Pittsburgh

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2025-04-15
Est. Completion 2026-03-27
Phase Phase 1

Sponsor

Merck Sharp & Dohme

558 total trials

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What the Registry Record Tells You About NCT06580587

The ClinicalTrials.gov registry entry for NCT06580587 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower). The listed sponsor is Merck Sharp & Dohme, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which MK-8527 is the first listed.

NCT06580587 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Missouri, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT06580587 about?

NCT06580587 is a clinical study titled "A Study of MK-8527 in Healthy Lactating Female Participants (MK-8527-009)". The goal of this study is to learn how MK-8527 moves through the healthy person's body over time. Researchers will measure for the amount of MK-8527 in breast milk that the baby will receive at many time points.

What is the current status of trial NCT06580587?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2025-04-15. Estimated completion is 2026-03-27.

What conditions does trial NCT06580587 study?

This clinical trial studies the following conditions: Healthy, HIV Pre-exposure Prophylaxis.

What interventions are being tested in trial NCT06580587?

The interventions under investigation include: MK-8527 (DRUG).

Who is sponsoring clinical trial NCT06580587?

This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06580587 being conducted?

This trial has 2 study locations across Missouri, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.