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NCT06544408 · ClinicalTrials.gov registry record · NA

Rapid Treatment of PTSD With Accelerated Non-Invasive Brain Stimulation

A NA study of Post Traumatic Stress Disorder and Traumatic Brain Injury, sponsored by Florida State University.

Recruiting
Registry status
NA
Development phase
132
Enrollment target
1
Study location

NCT06544408: Recruiting NA study of Post Traumatic Stress Disorder and Traumatic Brain Injury, sponsored by Florida State University.

NCT06544408 is a NA study of Post Traumatic Stress Disorder and Traumatic Brain Injury that is actively recruiting participants, run by Florida State University. The registered enrollment target is 132 participants, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06544408, a NA study of Post Traumatic Stress Disorder and Traumatic Brain Injury, is actively recruiting participants, sponsored by Florida State University.

RECRUITING
Registry status
NA
Development phase
132 participants
Enrollment target
1
Study location

Study Summary

This study will test the clinical efficacy of an accelerated TMS (accel-TMS) protocol that rapidly addresses PTSD symptoms with 1 week (25 sessions over 5 days) of condensed treatment.

Primary Outcome

CAPS-V is a 30-item clinical interview used to diagnose PTSD as well as monitor PTSD symptoms. Questions address the traumatic event(s), symptom duration, subjective distress, impact on functioning, dissociation, and symptom improvement since last evaluation. During the Acute Phase, CAPS-V will be used to determine the rapid efficacy of left dl-PFC accel-TMS compared to sham accel-TMS at approximately one-week post-treatment.

Interventions

  • DEVICE Cool B70 AP Coil - Active (dl-PFC)
  • DEVICE Cool B70 AP Coil- Sham (dl-PFC)
  • DEVICE Cool D-B80 AP Coil - Active (dm-PFC)
  • DEVICE Cool D-B80 AP Coil - Sham (dm-PFC)
  • DEVICE Cool B70 Treatment Coil - Active Only

Study Locations (1)

Florida

  • Florida State University - Tallahassee

Trial Details

FieldValue
Enrollment Target 132 participants
Start Date 2024-11-06
Est. Completion 2028-12-30
Phase NA
Florida State University

219 total trials

What NCT06544408 shows while recruiting

NCT06544408 is an interventional study that assigns participants to a tested intervention. The registered 132 participants enrollment target is mid-sized for trials with a published cap, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (80% lower).

The record links to 2 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 5 interventions - of which Cool B70 AP Coil - Active (dl-PFC) is the first listed.

NCT06544408 reports a single indexed study location in Florida.

Frequently Asked Questions

What is clinical trial NCT06544408 about?

NCT06544408 is a clinical study titled "Rapid Treatment of PTSD With Accelerated Non-Invasive Brain Stimulation". This study will test the clinical efficacy of an accelerated TMS (accel-TMS) protocol that rapidly addresses PTSD symptoms with 1 week (25 sessions over 5 days) of condensed treatment.

What is the current status of trial NCT06544408?

This trial is currently recruiting. It is a NA study. The enrollment target is 132 participants. The study started on 2024-11-06. Estimated completion is 2028-12-30.

What conditions does trial NCT06544408 study?

This clinical trial studies the following conditions: Post Traumatic Stress Disorder, Traumatic Brain Injury.

What interventions are being tested in trial NCT06544408?

The interventions under investigation include: Cool B70 AP Coil - Active (dl-PFC) (DEVICE), Cool B70 AP Coil- Sham (dl-PFC) (DEVICE), Cool D-B80 AP Coil - Active (dm-PFC) (DEVICE), Cool D-B80 AP Coil - Sham (dm-PFC) (DEVICE), Cool B70 Treatment Coil - Active Only (DEVICE).

Who is sponsoring clinical trial NCT06544408?

This trial is sponsored by Florida State University, which has 219 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06544408 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Post Traumatic Stress Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06544408's enrollment target sits among peer trials

132 91st of 262 higher than 172 of 262 other Post Traumatic Stress Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06544408, the US trial registry maintained by the National Library of Medicine. NCT06544408 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.