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NCT06479161 · ClinicalTrials.gov registry record · Phase 2
Effects of Oral Tranexamic Acid Following Total Knee Arthroplasty
A Phase 2 study of Postoperative Pain, sponsored by Matthew Grosso, MD.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT06479161: Recruiting Phase 2 study of Postoperative Pain, sponsored by Matthew Grosso, MD.
NCT06479161 is a Phase 2 study of Postoperative Pain that is actively recruiting participants, run by Matthew Grosso, MD. The registered enrollment target is 80 participants, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (65% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06479161, a Phase 2 study of Postoperative Pain, is actively recruiting participants, sponsored by Matthew Grosso, MD.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary purpose of this study is to evaluate postoperative pain. Secondary outcomes evaluated in this study will include range of motion (ROM), opioid consumption, and ambulation. Each outcome measure will be evaluated, oral tranexamic acid (TXA) in the experiment arm and placebo in the control arm, after total knee arthroplasty (TKA) at postoperative days 0-3, and weeks 1, 2, 6, and 12.
Primary Outcome
Patient reported pain score from 0 to 10 where 0 is no pain and 10 is the most pain. Higher scores are a worse outcome.
Conditions Studied
Interventions
- DRUG Tranexamic acid
Study Locations (1)
Connecticut
- Trinity Health Of New England/CT Joint Replacement Institute - Hartford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2024-06-10 |
| Est. Completion | 2025-03-30 |
| Phase | Phase 2 |
What NCT06479161 shows while recruiting
NCT06479161 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (65% lower).
The record links to 1 condition, with Postoperative Pain appearing as the primary indexed condition, and to 1 intervention - of which Tranexamic acid is the first listed.
NCT06479161 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT06479161 about?
NCT06479161 is a clinical study titled "Effects of Oral Tranexamic Acid Following Total Knee Arthroplasty". The primary purpose of this study is to evaluate postoperative pain. Secondary outcomes evaluated in this study will include range of motion (ROM), opioid consumption, and ambulation. Each outcome measure will be evaluated, oral tranexamic acid (TXA) in the experiment arm and placebo in the control ...
What is the current status of trial NCT06479161?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2024-06-10. Estimated completion is 2025-03-30.
What conditions does trial NCT06479161 study?
This clinical trial studies the following conditions: Postoperative Pain.
What interventions are being tested in trial NCT06479161?
The interventions under investigation include: Tranexamic acid (DRUG).
Who is sponsoring clinical trial NCT06479161?
This trial is sponsored by Matthew Grosso, MD, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06479161 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06479161's enrollment target sits among peer trials
80 69th of 120 higher than 47 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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