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NCT06426641 · ClinicalTrials.gov registry record
Polyethylene Wear Particle Analysis of TKA
A clinical trial of Total Knee Arthroplasty and Wear of Articular Bearing Surface of Prosthetic Joint, sponsored by Osaka Metropolitan University.
- Active
- Registry status
- 90
- Enrollment target
- 2
- Study locations
NCT06426641: Active study of Total Knee Arthroplasty and Wear of Articular Bearing Surface of Prosthetic Joint, sponsored by Osaka Metropolitan University.
NCT06426641 is a study of Total Knee Arthroplasty and Wear of Articular Bearing Surface of Prosthetic Joint that is active but no longer recruiting, run by Osaka Metropolitan University. The registered enrollment target is 90 participants, below the 292-participant average among 29 other Total Knee Arthroplasty trials with a reported enrollment target (69% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06426641, a study of Total Knee Arthroplasty and Wear of Articular Bearing Surface of Prosthetic Joint, is active but no longer recruiting, sponsored by Osaka Metropolitan University.
- ACTIVE NOT RECRUITING
- Registry status
- 90 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this study was to investigate whether polyethylene (Vitamin E-containing polyethylene), which has been newly introduced and widely used clinically as a biomaterial for tibial inserts in total knee arthroplasty, but whose mid- to long-term clinical results are still unknown, is more effective than conventional polyethylene. Our goal is to clarify through an international multi-center joint study using in vivo polyethylene wear particle analysis, which the investigators developed as a method to provide early feedback, as to whether polyethylene wear debris production in vivo can be reduced.
Primary Outcome
counts / g (tissue sample)
Conditions Studied
Interventions
- DEVICE Polyethylene
Study Locations (2)
Minnesota
- Mayo Clinic - Rochester
Other
- Osaka Metroplitan Univerity - Osaka
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2023-12-05 |
| Est. Completion | 2028-12-31 |
What the registry record for NCT06426641 still lists
NCT06426641 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 292-participant average among 29 other Total Knee Arthroplasty trials with a reported enrollment target (69% lower).
The record links to 2 conditions, with Total Knee Arthroplasty appearing as the primary indexed condition, and to 1 intervention - of which Polyethylene is the first listed.
NCT06426641 reports a single indexed study location in Minnesota, Other.
Frequently Asked Questions
What is clinical trial NCT06426641 about?
NCT06426641 is a clinical study titled "Polyethylene Wear Particle Analysis of TKA". The purpose of this study was to investigate whether polyethylene (Vitamin E-containing polyethylene), which has been newly introduced and widely used clinically as a biomaterial for tibial inserts in total knee arthroplasty, but whose mid- to long-term clinical results are still unknown, is more ef...
What is the current status of trial NCT06426641?
This trial is currently active not recruiting. The enrollment target is 90 participants. The study started on 2023-12-05. Estimated completion is 2028-12-31.
What conditions does trial NCT06426641 study?
This clinical trial studies the following conditions: Total Knee Arthroplasty, Wear of Articular Bearing Surface of Prosthetic Joint.
What interventions are being tested in trial NCT06426641?
The interventions under investigation include: Polyethylene (DEVICE).
Who is sponsoring clinical trial NCT06426641?
This trial is sponsored by Osaka Metropolitan University, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06426641 being conducted?
This trial has 2 study locations across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06426641's enrollment target sits among peer trials
90 20th of 29 higher than 10 of 29 other Total Knee Arthroplasty trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Total Knee Arthroplasty trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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