Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05288803 · ClinicalTrials.gov registry record
Improving Rehabilitation for Veterans After Total Knee Arthroplasty Using Individualized Recovery Trajectories
A clinical trial of Total Knee Arthroplasty, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- 200
- Enrollment target
- 2
- Study locations
NCT05288803: Recruiting study of Total Knee Arthroplasty, sponsored by VA Office of Research and Development.
NCT05288803 is a study of Total Knee Arthroplasty that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 200 participants, below the 288-participant average among 29 other Total Knee Arthroplasty trials with a reported enrollment target (31% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05288803, a study of Total Knee Arthroplasty, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- 200 participants
- Enrollment target
- 2
- Study locations
Study Summary
This study will examine the impact of a new clinical decision support tool for rehabilitation after total knee arthroplasty (TKA). Typically, TKA rehabilitation is generic with most patients receiving the same dosage and contents of rehabilitation despite notable diversity among patients who undergo TKA. The investigators clinical support decision tool is designed to help physical therapists tailor rehabilitation treatments and dosages to the individual needs, goals, and preferences of Veterans recovering from TKA. This study has the potential to improve Veterans' functional recovery after TKA, while simultaneously reducing the average number of physical therapy visits Veterans attend after surgery by tailoring rehabilitation dosage based upon need. This will ensure the Veterans Health Administration (VHA) has the resources and capacity to provide adequate rehabilitation to every Veteran seeking TKA in the VHA system. Additionally, if successful, this clinical decision support tool could be used to improve outcomes and access for additional patient populations in the future.
Primary Outcome
The KOOS-JR is a patient-reported measure of physical function developed specifically for patients with total knee arthroplasty. It can be completed quickly (only 7 items) and has established validity, reliability, and responsiveness. KOOS JR will be assessed preoperatively at baseline and re-assessed at 90 (primary timepoint) and 180 days after TKA surgery. KOOS JR will also be assessed postoperatively throughout participants' rehabilitation episode at approximately 2-week intervals up to 180 d
Conditions Studied
Interventions
- OTHER Clinical decision support tool (CDS tool)
Study Locations (2)
Colorado
- Rocky Mountain Regional VA Medical Center, Aurora, CO - Aurora
Pennsylvania
- VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2022-04-01 |
| Est. Completion | 2026-09-30 |
What NCT05288803 shows while recruiting
NCT05288803 is an observational study that tracks outcomes without assigning an intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 288-participant average among 29 other Total Knee Arthroplasty trials with a reported enrollment target (31% lower).
The record links to 1 condition, with Total Knee Arthroplasty appearing as the primary indexed condition, and to 1 intervention - of which Clinical decision support tool (CDS tool) is the first listed.
NCT05288803 reports a single indexed study location in Colorado, Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05288803 about?
NCT05288803 is a clinical study titled "Improving Rehabilitation for Veterans After Total Knee Arthroplasty Using Individualized Recovery Trajectories". This study will examine the impact of a new clinical decision support tool for rehabilitation after total knee arthroplasty (TKA). Typically, TKA rehabilitation is generic with most patients receiving the same dosage and contents of rehabilitation despite notable diversity among patients who undergo...
What is the current status of trial NCT05288803?
This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2022-04-01. Estimated completion is 2026-09-30.
What conditions does trial NCT05288803 study?
This clinical trial studies the following conditions: Total Knee Arthroplasty.
What interventions are being tested in trial NCT05288803?
The interventions under investigation include: Clinical decision support tool (CDS tool) (OTHER).
Who is sponsoring clinical trial NCT05288803?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05288803 being conducted?
This trial has 2 study locations across Colorado, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Total Knee Arthroplasty
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05288803's enrollment target sits among peer trials
200 6th of 29 higher than 22 of 29 other Total Knee Arthroplasty trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Total Knee Arthroplasty trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Intraoperative VR for Older Patients Undergoing TKA
RECRUITING · NA
-
A Prospective, Randomized Parallel Group Study of the Efficacy of Vancomycin Administered Through Intraarticular Injection Versus Intraosseous Injection Versus Intravenous Infusion in Patients Undergoing Total Knee Arthroplasty
RECRUITING · Phase 4
-
Investigating Patient Satisfaction With Smart Knee Implants
RECRUITING · NA
-
Medrol Dosepak for Outpatient Total Knee Arthroplasty
RECRUITING · Phase 4
-
Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty
RECRUITING · NA
-
Minimal Sedation During Knee Replacement Surgery
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00107289 · 200 participants · Phase 2
Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma
- NCT00109174 · 200 participants · NA
MRS Measurement of Glutamate and GABA Metabolism in Brain
- NCT00177268 · 200 participants
Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research
- NCT00493688 · 200 participants
A Study to Determine Whether Perioperative Energy Dynamics Correlates With Postoperative Outcomes
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI