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NCT06358677 · ClinicalTrials.gov registry record · Phase 2

Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Patients With Solid Tumors

A Phase 2 study of Metastatic Solid Tumor and Locally Advanced Solid Tumor, sponsored by University of Utah.

Recruiting
Registry status
Phase 2
Development phase
25
Enrollment target
1
Study location

NCT06358677 is a Phase 2 study of Metastatic Solid Tumor and Locally Advanced Solid Tumor that is actively recruiting participants, run by University of Utah. The registered enrollment target is 25 participants, below the 192-participant average among 52 other Metastatic Solid Tumor trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06358677, a Phase 2 study of Metastatic Solid Tumor and Locally Advanced Solid Tumor, is actively recruiting participants, sponsored by University of Utah.

RECRUITING
Registry status
Phase 2
Development phase
25 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to learn if using topical tretinoin will help patients with solid tumors who are experiencing an acneiform rash as a side effect of their treatment. Researchers will compare the use of tretinoin on one side of the face to the use of a placebo on the other side of the face to see if there is an impact.

Interventions

  • OTHER Placebo
  • DRUG Topical Tretinoin

Study Locations (1)

Utah

  • Huntsman Cancer Institute at University of Utah - Salt Lake City

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2025-02-19
Est. Completion 2029-07
Phase Phase 2

Sponsor

University of Utah

818 total trials

What the Registry Record Tells You About NCT06358677

The ClinicalTrials.gov registry entry for NCT06358677 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 192-participant average among 52 other Metastatic Solid Tumor trials with a reported enrollment target (87% lower). The listed sponsor is University of Utah, which has 818 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Metastatic Solid Tumor appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06358677 reports 1 study location spanning 1 distinct geographic area - top geographies include Utah.

Frequently Asked Questions

What is clinical trial NCT06358677 about?

NCT06358677 is a clinical study titled "Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Patients With Solid Tumors". The goal of this clinical trial is to learn if using topical tretinoin will help patients with solid tumors who are experiencing an acneiform rash as a side effect of their treatment. Researchers will compare the use of tretinoin on one side of the face to the use of a placebo on the other side of ...

What is the current status of trial NCT06358677?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2025-02-19. Estimated completion is 2029-07.

What conditions does trial NCT06358677 study?

This clinical trial studies the following conditions: Metastatic Solid Tumor, Locally Advanced Solid Tumor.

What interventions are being tested in trial NCT06358677?

The interventions under investigation include: Placebo (OTHER), Topical Tretinoin (DRUG).

Who is sponsoring clinical trial NCT06358677?

This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06358677 being conducted?

This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.