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NCT05673928 · ClinicalTrials.gov registry record · Phase 2
A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)
A Phase 2 study of Brain Metastases and Metastatic Solid Tumor, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT05673928: Recruiting Phase 2 study of Brain Metastases and Metastatic Solid Tumor, sponsored by M.D. Anderson Cancer Center.
NCT05673928 is a Phase 2 study of Brain Metastases and Metastatic Solid Tumor that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 30 participants, below the 213-participant average among 67 other Brain Metastases trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05673928, a Phase 2 study of Brain Metastases and Metastatic Solid Tumor, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
To learn if the study drugs, tucatinib and adotrastuzumab emtansine (T-DM1), can help to control solid tumors that have spread to the brain.
Conditions Studied
Interventions
- DRUG Trastuzumab emtansine
- DRUG Tucatinib
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2023-05-16 |
| Est. Completion | 2029-03-01 |
| Phase | Phase 2 |
What NCT05673928 shows while recruiting
NCT05673928 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 213-participant average among 67 other Brain Metastases trials with a reported enrollment target (86% lower).
The record links to 2 conditions, with Brain Metastases appearing as the primary indexed condition, and to 2 interventions - of which Trastuzumab emtansine is the first listed.
NCT05673928 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05673928 about?
NCT05673928 is a clinical study titled "A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)". To learn if the study drugs, tucatinib and adotrastuzumab emtansine (T-DM1), can help to control solid tumors that have spread to the brain.
What is the current status of trial NCT05673928?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2023-05-16. Estimated completion is 2029-03-01.
What conditions does trial NCT05673928 study?
This clinical trial studies the following conditions: Brain Metastases, Metastatic Solid Tumor.
What interventions are being tested in trial NCT05673928?
The interventions under investigation include: Trastuzumab emtansine (DRUG), Tucatinib (DRUG).
Who is sponsoring clinical trial NCT05673928?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05673928 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Brain Metastases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05673928's enrollment target sits among peer trials
30 43rd of 67 higher than 24 of 67 other Brain Metastases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Brain Metastases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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