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NCT04059172 · ClinicalTrials.gov registry record · Early Phase 1

Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain Management

A Early Phase 1 study of Pain, Orofacial, sponsored by University of Colorado, Denver.

Recruiting
Registry status
Early Phase 1
Development phase
375
Enrollment target
1
Study location

NCT04059172 is a Early Phase 1 study of Pain, Orofacial that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 375 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT04059172, a Early Phase 1 study of Pain, Orofacial, is actively recruiting participants, sponsored by University of Colorado, Denver.

RECRUITING
Registry status
Early Phase 1
Development phase
375 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to compare the effectiveness of a combined ibuprofen and acetaminophen regimen in controlling discomfort for 4 days after initial orthodontic appliance placement as compared to ibuprofen alone or a placebo. The hypothesis is that combined ibuprofen and acetaminophen therapy will effectively provide better pain control than ibuprofen alone or a placebo after orthodontic appliance placement.

Conditions Studied

Interventions

  • DRUG Placebo oral tablet
  • DRUG Ibuprofen 200 mg and acetaminphen 650 mg
  • DRUG Ibuprofen 200 mg

Study Locations (1)

Colorado

  • University of Colorado, School of Dental Medicine - Aurora

Trial Details

FieldValue
Enrollment Target 375 participants
Start Date 2019-12-10
Est. Completion 2028-01-01
Phase Early Phase 1

Sponsor

University of Colorado, Denver

1,283 total trials

What the Registry Record Tells You About NCT04059172

The ClinicalTrials.gov registry entry for NCT04059172 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 375 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pain, Orofacial appearing as the primary indexed condition, and to 3 interventions - of which Placebo oral tablet is the first listed.

NCT04059172 reports 1 study location spanning 1 distinct geographic area - top geographies include Colorado.

Frequently Asked Questions

What is clinical trial NCT04059172 about?

NCT04059172 is a clinical study titled "Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain Management". The purpose of this study is to compare the effectiveness of a combined ibuprofen and acetaminophen regimen in controlling discomfort for 4 days after initial orthodontic appliance placement as compared to ibuprofen alone or a placebo. The hypothesis is that combined ibuprofen and acetaminophen ther...

What is the current status of trial NCT04059172?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 375 participants. The study started on 2019-12-10. Estimated completion is 2028-01-01.

What conditions does trial NCT04059172 study?

This clinical trial studies the following conditions: Pain, Orofacial.

What interventions are being tested in trial NCT04059172?

The interventions under investigation include: Placebo oral tablet (DRUG), Ibuprofen 200 mg and acetaminphen 650 mg (DRUG), Ibuprofen 200 mg (DRUG).

Who is sponsoring clinical trial NCT04059172?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04059172 being conducted?

This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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