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RECRUITING Phase 2

A Study of sEphB4-HSA in Kaposi Sarcoma

NCT03993106 · View on ClinicalTrials.gov ↗

Study Summary

sEphB-HSA may prevent tumor cells from multiplying and blocks several compounds that promote the growth of blood vessels that bring nutrients to the tumor. The purpose of this study is to learn if sEphB4-HSA will decrease the number or size of Kaposi sarcoma lesions in people.

Conditions Studied

Interventions

  • DRUG sEphB4-HSA

Study Locations (3)

California

  • AIDS Healthcare Foundation — Beverly Hills

Florida

  • CAN (Community AIDS Network) Community Health — Sarasota

Texas

  • UT Southwestern Medical Center — Dallas

Trial Details

FieldValue
Enrollment Target 65 participants
Start Date 2020-09-17
Est. Completion 2025-06
Phase Phase 2

Sponsor

Vasgene Therapeutics

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03993106

The ClinicalTrials.gov registry entry for NCT03993106 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 65 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vasgene Therapeutics, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Kaposi Sarcoma appearing as the primary indexed condition, and to 1 intervention — of which sEphB4-HSA is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03993106 reports 3 study locations spanning 3 distinct geographic areas — top geographies include California, Florida, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03993106 about?

NCT03993106 is a clinical study titled "A Study of sEphB4-HSA in Kaposi Sarcoma". sEphB-HSA may prevent tumor cells from multiplying and blocks several compounds that promote the growth of blood vessels that bring nutrients to the tumor. The purpose of this study is to learn if sEphB4-HSA will decrease the number or size of Kaposi sarcoma lesions in people.

What is the current status of trial NCT03993106?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 65 participants. The study started on 2020-09-17. Estimated completion is 2025-06.

What conditions does trial NCT03993106 study?

This clinical trial studies the following conditions: Kaposi Sarcoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03993106?

The interventions under investigation include: sEphB4-HSA (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03993106?

This trial is sponsored by Vasgene Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03993106 being conducted?

This trial has 3 study locations across California, Florida, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial