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NCT05617898 · ClinicalTrials.gov registry record · NA

Determining the Role of Social Reward Learning in Social Anhedonia

A NA study of Psychosis, sponsored by University of Alabama at Birmingham.

Recruiting
Registry status
NA
Development phase
152
Enrollment target
2
Study locations

NCT05617898: Recruiting NA study of Psychosis, sponsored by University of Alabama at Birmingham.

NCT05617898 is a NA study of Psychosis that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 152 participants, below the 174-participant average among 35 other Psychosis trials with a reported enrollment target (13% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05617898, a NA study of Psychosis, is actively recruiting participants, sponsored by University of Alabama at Birmingham.

RECRUITING
Registry status
NA
Development phase
152 participants
Enrollment target
2
Study locations

Study Summary

This is a clinical trial study that aims to evaluate the specificity of the relationship between reduced sensitivity to social reward and social anhedonia at both behavioral and neural levels. Individuals who recently experienced their first-episode psychosis will be recruited. Participants will be randomized 1:1 to motivational interviewing or a time- and format-matched control probe. At pre- and post-probe, participants will perform two social reward learning tasks in the scanner. With this design feature, we will examine the relationship between sensitivity to social reward and reduced subjective experience of social pleasure at both the behavioral and neural levels.

Primary Outcome

Response bias is defined as the likelihood of making one response, such as the frequently rewarded stimulus, more than the other response during the perceptual social reward learning task

Conditions Studied

Interventions

  • BEHAVIORAL Motivational Interviewing
  • BEHAVIORAL Nutrition Didactic Training

Study Locations (2)

Alabama

  • University of Alabama at Birmingham - Birmingham

California

  • University of California Los Angeles - Los Angeles

Trial Details

FieldValue
Enrollment Target 152 participants
Start Date 2023-06-14
Est. Completion 2027-11
Phase NA
University of Alabama at Birmingham

1,160 total trials

What NCT05617898 shows while recruiting

NCT05617898 is an interventional study that assigns participants to a tested intervention. The registered 152 participants enrollment target is mid-sized for trials with a published cap, below the 174-participant average among 35 other Psychosis trials with a reported enrollment target (13% lower).

The record links to 1 condition, with Psychosis appearing as the primary indexed condition, and to 2 interventions - of which Motivational Interviewing is the first listed.

NCT05617898 reports a single indexed study location in Alabama, California.

Frequently Asked Questions

What is clinical trial NCT05617898 about?

NCT05617898 is a clinical study titled "Determining the Role of Social Reward Learning in Social Anhedonia". This is a clinical trial study that aims to evaluate the specificity of the relationship between reduced sensitivity to social reward and social anhedonia at both behavioral and neural levels. Individuals who recently experienced their first-episode psychosis will be recruited. Participants will be ...

What is the current status of trial NCT05617898?

This trial is currently recruiting. It is a NA study. The enrollment target is 152 participants. The study started on 2023-06-14. Estimated completion is 2027-11.

What conditions does trial NCT05617898 study?

This clinical trial studies the following conditions: Psychosis.

What interventions are being tested in trial NCT05617898?

The interventions under investigation include: Motivational Interviewing (BEHAVIORAL), Nutrition Didactic Training (BEHAVIORAL).

Who is sponsoring clinical trial NCT05617898?

This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05617898 being conducted?

This trial has 2 study locations across Alabama, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Psychosis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05617898's enrollment target sits among peer trials

152 8th of 35 higher than 27 of 35 other Psychosis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Psychosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05617898, the US trial registry maintained by the National Library of Medicine. NCT05617898 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.