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NCT05892718 · ClinicalTrials.gov registry record · Phase 1

A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors

A Phase 1 study of Advanced Solid Tumor and Refractory Non-Hodgkin Lymphoma, sponsored by FBD Biologics Limited.

Recruiting
Registry status
Phase 1
Development phase
80
Enrollment target
8
Study locations

NCT05892718 is a Phase 1 study of Advanced Solid Tumor and Refractory Non-Hodgkin Lymphoma that is actively recruiting participants, run by FBD Biologics Limited. The registered enrollment target is 80 participants, below the 193-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target (59% lower). The trial reports 8 study locations across 6 states.

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The verdict

NCT05892718, a Phase 1 study of Advanced Solid Tumor and Refractory Non-Hodgkin Lymphoma, is actively recruiting participants, sponsored by FBD Biologics Limited.

RECRUITING
Registry status
Phase 1
Development phase
80 participants
Enrollment target
8
Study locations

Study Summary

The purpose of this study is to find out whether IV injection of HCB101 is an effective treatment for different types of advanced solid tumors or relapsed and refractory non-Hodgkin lymphoma and what side effects (unwanted effects) may occur in subjects aged 18 years old and above.

Interventions

  • DRUG HCB101

Study Locations (8)

Other

  • Taipei Medical University - Shuang Ho Hospital, Ministry of Health and Welfare - New Taipei City
  • National Taiwan University Hospital - Taipei
  • Taipei Veterans General Hospital - Taipei

Florida

  • Hematology-Oncology Associates of the Treasure Coast - Port Saint Lucie

North Carolina

  • Carolina BioOncology - Huntersville

South Carolina

  • Greenville Hospital System University Medical Center (ITOR) - Greenville

Texas

  • UT Southwestern Medical Center - Dallas

Zhejiang

  • Hangzhou First People's Hospital - Hangzhou

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2023-10-02
Est. Completion 2029-11-15
Phase Phase 1

Sponsor

FBD Biologics Limited

2 total trials

What the Registry Record Tells You About NCT05892718

The ClinicalTrials.gov registry entry for NCT05892718 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 193-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target (59% lower). The listed sponsor is FBD Biologics Limited, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Advanced Solid Tumor appearing as the primary indexed condition, and to 1 intervention - of which HCB101 is the first listed.

NCT05892718 reports 8 study locations spanning 6 distinct geographic areas - top geographies include Other, Florida, North Carolina.

Frequently Asked Questions

What is clinical trial NCT05892718 about?

NCT05892718 is a clinical study titled "A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors". The purpose of this study is to find out whether IV injection of HCB101 is an effective treatment for different types of advanced solid tumors or relapsed and refractory non-Hodgkin lymphoma and what side effects (unwanted effects) may occur in subjects aged 18 years old and above.

What is the current status of trial NCT05892718?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2023-10-02. Estimated completion is 2029-11-15.

What conditions does trial NCT05892718 study?

This clinical trial studies the following conditions: Advanced Solid Tumor, Refractory Non-Hodgkin Lymphoma.

What interventions are being tested in trial NCT05892718?

The interventions under investigation include: HCB101 (DRUG).

Who is sponsoring clinical trial NCT05892718?

This trial is sponsored by FBD Biologics Limited, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05892718 being conducted?

This trial has 8 study locations across Florida, North Carolina, South Carolina, Texas, Zhejiang. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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